Control mechanism of JAK/STAT signal transduction pathway. - Wikidata - awgldk - TriplyDB

Control mechanism of JAK/STAT signal transduction pathway.

Control mechanism of JAK/STAT signal transduction pathway.

http://www.wikidata.org/entity/Q44277958

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UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity Quantitative and logic modelling of molecular and gene networks A unique transformation from ordinary differential equations to reaction networks Modeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expression A simple work flow for biologically inspired model reduction--application to early JAK-STAT signaling.Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control.Comparative analysis of the JAK/STAT signaling through erythropoietin receptor and thrombopoietin receptor using a systems approach.Systematic identifiability testing for unambiguous mechanistic modeling--application to JAK-STAT, MAP kinase, and NF-kappaB signaling pathway models Using chemical organization theory for model checking.The benzoxathiolone LYR-71 down-regulates interferon-gamma-inducible pro-inflammatory genes by uncoupling tyrosine phosphorylation of STAT-1 in macrophages Immune response modeling of interferon beta-pretreated influenza virus-infected human dendritic cells.Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling.Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.Understanding dynamics using sensitivity analysis: caveat and solution Inferring relevant control mechanisms for interleukin-12 signaling in naïve CD4+ T cells.Modeling and dynamical analysis of virus-triggered innate immune signaling pathways.A strategy to study pathway cross-talks of cells under repetitive exposure to stimuli.Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling.Transient oscillatory dynamics of interferon beta signaling in macrophages Computational modeling of mammalian signaling networks.Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.Model selection in systems biology depends on experimental design.Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation Hierarchical feedback modules and reaction hubs in cell signaling networks.Dynamic Redox Regulation of IL-4 Signaling.Investigating the Role of TNF-α and IFN-γ Activation on the Dynamics of iNOS Gene Expression in LPS Stimulated Macrophages In silico modeling of shear-stress-induced nitric oxide production in endothelial cells through systems biology STAT3 as a target for inducing apoptosis in solid and hematological tumors Computational models of the JAK1/2-STAT1 signaling A mathematical model for dynamics of CD40 clustering.Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype.Live cell imaging and systems biology.Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapy.Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/STAT signaling.Proteome profiling reveals potential toxicity and detoxification pathways following exposure of BEAS-2B cells to engineered nanoparticle titanium dioxide.Spatio-temporal dynamics of a cell signal pathway with negative feedbacks: the MAPK/ERK pathway.The JAK-STAT signaling network in the human B-cell: an extreme signaling pathway analysis.Positive receptor feedback during lineage commitment can generate ultrasensitivity to ligand and confer robustness to a bistable switch.A multiscale model of interleukin-6-mediated immune regulation in Crohn's disease and its application in drug discovery and development.Activation of Janus kinase/signal transducers and activators of transcription pathway involved in megakaryocyte proliferation induced by vanadium resembles some aspects of essential thrombocythemia.

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P2860

Control mechanism of JAK/STAT signal transduction pathway.

http://www.wikidata.org/entity/Q44277958

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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name

Control mechanism of JAK/STAT signal transduction pathway.

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Control mechanism of JAK/STAT signal transduction pathway.

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type

label

Control mechanism of JAK/STAT signal transduction pathway.

@en

Control mechanism of JAK/STAT signal transduction pathway.

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prefLabel

Control mechanism of JAK/STAT signal transduction pathway.

@en

Control mechanism of JAK/STAT signal transduction pathway.

@nl

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S0014-5793(02)03842-5

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P1476

Control mechanism of JAK/STAT signal transduction pathway.

@en

P2093

Akihiko Yoshimura

http://www.w3.org/2001/XMLSchema#string

Akiko Joo

http://www.w3.org/2001/XMLSchema#string

Satoru Shiono

http://www.w3.org/2001/XMLSchema#string

Satoshi Yamada

http://www.w3.org/2001/XMLSchema#string

P2860

Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads

Suppressors of cytokine signaling (SOCS): inhibitors of the JAK/STAT pathway

Identification of a nuclear Stat1 protein tyrosine phosphatase

A new protein containing an SH2 domain that inhibits JAK kinases

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

Negative regulation of cytokine signaling pathways

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

The STAT family of proteins in cytokine signaling.

The Jak-STAT pathway.

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190-196

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scholarly article

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10.1016/S0014-5793(02)03842-5

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12527385

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