Coupling efficacy and selectivity of the human mu-opioid receptor expressed as receptor-Galpha fusion proteins in Escherichia coli.
about
Ligand-directed functional selectivity at the mu opioid receptor revealed by label-free integrative pharmacology on-targetTuning microbial hosts for membrane protein production.RGSZ1 and GAIP regulate mu- but not delta-opioid receptors in mouse CNS: role in tachyphylaxis and acute tolerance.Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently.The olfactory G protein G(alphaolf) possesses a lower GDP-affinity and deactivates more rapidly than G(salphashort): consequences for receptor-coupling and adenylyl cyclase activation.Functional coupling with Galpha(q) and Galpha(i1) protein subunits promotes high-affinity agonist binding to the neurotensin receptor NTS-1 expressed in Escherichia coli.Interaction of the muscarinic acetylcholine receptor M₂ subtype with G protein Gα(i/o) isotypes and Gβγ subunits as studied with the maltose-binding protein-M₂-Gα(i/o) fusion proteins expressed in Escherichia coli.
P2860
Q28477403-476260CF-7656-46DB-A34A-02875D6A1A3AQ33596003-4D6F6CA8-F828-4EB8-9606-364880233248Q38344148-A8B3E185-C955-44B3-89AB-9EB229F60EDEQ40724494-BB120F4F-0E81-4372-8141-7723EC17E261Q40791394-C8E4C940-9E30-4A24-91A9-2AFB1E317AE0Q43564870-0FC77432-A928-40AF-8238-3C9724AD3C5CQ46886289-8C242ED1-9594-4521-BEC7-47C789F20D79
P2860
Coupling efficacy and selectivity of the human mu-opioid receptor expressed as receptor-Galpha fusion proteins in Escherichia coli.
description
2000 nî lūn-bûn
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name
Coupling efficacy and selectiv ...... proteins in Escherichia coli.
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Coupling efficacy and selectiv ...... proteins in Escherichia coli.
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type
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Coupling efficacy and selectiv ...... proteins in Escherichia coli.
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Coupling efficacy and selectiv ...... proteins in Escherichia coli.
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Coupling efficacy and selectiv ...... proteins in Escherichia coli.
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Coupling efficacy and selectiv ...... proteins in Escherichia coli.
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P2860
P1476
Coupling efficacy and selectiv ...... n proteins in Escherichia coli
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10.1046/J.1471-4159.2000.0751190.X
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2000-09-01T00:00:00Z