Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.
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Pivotal roles of GM-CSF in autoimmunity and inflammationPotential benefits of therapeutic use of β2-adrenergic receptor agonists in neuroprotection and Parkinsonμs diseaseRole of neuroinflammation in neurodegenerative diseases (Review)Morphine protects against methylmercury intoxication: a role for opioid receptors in oxidative stress?Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.The extracellular signal-regulated kinase 1/2 pathway in neurological diseases: A potential therapeutic target (Review).Changes in the NMR metabolic profile of human microglial cells exposed to lipopolysaccharide or morphine.Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions.NADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice.Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia.Low dose dextromethorphan attenuates moderate experimental autoimmune encephalomyelitis by inhibiting NOX2 and reducing peripheral immune cells infiltration in the spinal cordA simple magnetic separation method for high-yield isolation of pure primary microgliaNaloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidaseOxidative stress and microglial cells in Parkinson's diseaseNeuroinflammation is a key player in Parkinson's disease and a prime target for therapy.The changing phenotype of microglia from homeostasis to diseasebeta2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway.β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway.Microglia induce neurotoxicity via intraneuronal Zn(2+) release and a K(+) current surge.Morphine: a protective or destructive role in neurons?Aqueous extract from the Withania somnifera leaves as a potential anti-neuroinflammatory agent: a mechanistic study.Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia.Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity.Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors.New concepts in white adipose tissue physiology.T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases.NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease.Morphine Attenuated the Cytotoxicity Induced by Arsenic Trioxide in H9c2 Cardiomyocytes.mu-opioid receptor-stimulated synthesis of reactive oxygen species is mediated via phospholipase D2.Morphine pre- and post-conditioning exacerbates apoptosis in rat hippocampus cells in a model of homocysteine-induced oxidative stress.μ-Opioid receptor attenuates Aβ oligomers-induced neurotoxicity through mTOR signaling.Life span extension in Drosophila melanogaster induced by morphine.A simplified approach for efficient isolation of functional microglial cells: Application for modeling neuroinflammatory responses in vitro.Microglial cells and Parkinson's disease.Antioxidants Protect against Arsenic Induced Mitochondrial Cardio-Toxicity.Substances in subthreshold concentrations under stress conditions can act as conditioned stimuli and trigger defense reactions.Morphine preconditioning protects against LPS-induced neuroinflammation and memory deficit.TGF-β1 Neuroprotection via Inhibition of Microglial Activation in a Rat Model of Parkinson's Disease.
P2860
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P2860
Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Microglia-mediated neurotoxici ...... ion of NADPH oxidase activity.
@en
Microglia-mediated neurotoxici ...... ion of NADPH oxidase activity.
@nl
type
label
Microglia-mediated neurotoxici ...... ion of NADPH oxidase activity.
@en
Microglia-mediated neurotoxici ...... ion of NADPH oxidase activity.
@nl
prefLabel
Microglia-mediated neurotoxici ...... ion of NADPH oxidase activity.
@en
Microglia-mediated neurotoxici ...... ion of NADPH oxidase activity.
@nl
P2093
P921
P1476
Microglia-mediated neurotoxici ...... tion of NADPH oxidase activity
@en
P2093
Belinda Wilson
Hung-Ming Wu
Kai Soo Tan
Patrick M Flood
P304
P356
10.4049/JIMMUNOL.179.2.1198
P407
P577
2007-07-01T00:00:00Z