Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
about
Frameshifting RNA pseudoknots: structure and mechanismAntibiotics that target protein synthesisMMB-GUI: a fast morphing method demonstrates a possible ribosomal tRNA translocation trajectory.Blasticidin S inhibits translation by trapping deformed tRNA on the ribosomeConnecting the kinetics and energy landscape of tRNA translocation on the ribosomeAminoglycoside activity observed on single pre-translocation ribosome complexes.The role of L1 stalk-tRNA interaction in the ribosome elongation cycleInterrupted catalysis: the EF4 (LepA) effect on back-translocation.tRNA dynamics on the ribosome during translation.Thermodynamic and kinetic insights into stop codon recognition by release factor 1.Spontaneous formation of the unlocked state of the ribosome is a multistep process.Cleavage of the sarcin-ricin loop of 23S rRNA differentially affects EF-G and EF-Tu bindingProbing translation with small-molecule inhibitorsA new view of protein synthesis: mapping the free energy landscape of the ribosome using single-molecule FRET.Polyamines accelerate codon recognition by transfer RNAs on the ribosome.Histidine 197 in release factor 1 is essential for a site binding and peptide releaseEF-G-independent reactivity of a pre-translocation-state ribosome complex with the aminoacyl tRNA substrate puromycin supports an intermediate (hybrid) state of tRNA bindingCorrelated conformational events in EF-G and the ribosome regulate translocation.Following movement of domain IV of elongation factor G during ribosomal translocation.Colicin E3 cleavage of 16S rRNA impairs decoding and accelerates tRNA translocation on Escherichia coli ribosomes.Ribosomal translocation: one step closer to the molecular mechanism.Movement of elongation factor G between compact and extended conformations.Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosomeTransfer RNA-mediated regulation of ribosome dynamics during protein synthesis.The hybrid state of tRNA binding is an authentic translation elongation intermediateThe conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesisFusidic acid targets elongation factor G in several stages of translocation on the bacterial ribosome.Functional role of the sarcin-ricin loop of the 23S rRNA in the elongation cycle of protein synthesis.Fluctuations of transfer RNAs between classical and hybrid statesNew insights into the enzymatic role of EF-G in ribosome recyclingIdentification of two distinct hybrid state intermediates on the ribosomeRotation of the head of the 30S ribosomal subunit during mRNA translocation.Contribution of intersubunit bridges to the energy barrier of ribosomal translocation.Role of hybrid tRNA-binding states in ribosomal translocation.Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation.Structural characterization of ribosome recruitment and translocation by type IV IRES.EF-G Activation by Phosphate AnalogsEnsemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.Quantitative studies of ribosome conformational dynamics.Elongation factor G initiates translocation through a power stroke
P2860
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P2860
Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
@en
Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
@nl
type
label
Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
@en
Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
@nl
prefLabel
Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
@en
Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
@nl
P2093
P1476
Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome.
@en
P2093
Jason S Feinberg
Sean M Studer
Simpson Joseph
P304
P356
10.1016/S0022-2836(03)00146-3
P407
P577
2003-03-01T00:00:00Z