Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart.
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Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiencySildenafil citrate increases myocardial cGMP content in rat heart, decreases its hypertrophic response to isoproterenol and decreases myocardial leak of creatine kinase and troponin TVascular endothelial dysfunction and pharmacological treatmentNitric oxide synthases in heart failureTherapeutic potential of PDE modulation in treating heart diseaseSirtuin 1 (SIRT1) activation mediates sildenafil induced delayed cardioprotection against ischemia-reperfusion injury in micePretreatment of sildenafil attenuates ischemia-reperfusion renal injury in ratsFiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuliPivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts.Inhibition of iNOS protects endothelial-dependent vasodilation in aged rats.Chronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling.PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells.Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation.Nitric oxide signalling and neuronal nitric oxide synthase in the heart under stress.Phosphodiesterase-5 inhibition mimics intermittent reoxygenation and improves cardioprotection in the hypoxic myocardium.Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect.Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury.Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts.Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Targeting cyclic nucleotide phosphodiesterase in the heart: therapeutic implications.Cyclic guanosine monophosphate signaling and phosphodiesterase-5 inhibitors in cardioprotection.Anti-inflammatory and cardioprotective effects of tadalafil in diabetic miceRole of microRNAs in cardiac preconditioningAdenosine A(1) receptor mediates delayed cardioprotective effect of sildenafil in mouse.Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfideSildenafil and vardenafil but not nitroglycerin limit myocardial infarction through opening of mitochondrial K(ATP) channels when administered at reperfusion following ischemia in rabbitsAttenuation of Doxorubicin-induced Cardiotoxicity by Tadalafil: A Long Acting Phosphodiesterase-5 Inhibitor.Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathwayThe role of phosphodiesterase inhibitors in the management of pulmonary vascular diseasesEmerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases.Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in PodocytesTadalafil, a Phosphodiesterase Inhibitor Protects Stem Cells over Longer Period Against Hypoxia/Reoxygenation Injury Through STAT3/PKG-I Signaling.L-Citrulline Protects Skeletal Muscle Cells from Cachectic Stimuli through an iNOS-Dependent Mechanism.PDE5 inhibitors as therapeutics for heart disease, diabetes and cancerCinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide.Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 PhosphorylationImpact of Mitochondrial Ca2+-Sensitive Potassium (mBKCa) Channels in Sildenafil-Induced Cardioprotection in Rats.Dietary inorganic nitrate alleviates doxorubicin cardiotoxicity: mechanisms and implications.Cardiac role of cyclic-GMP hydrolyzing phosphodiesterase type 5: from experimental models to clinical trials.
P2860
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P2860
Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Sildenafil induces delayed pre ...... endent pathway in mouse heart.
@en
Sildenafil induces delayed pre ...... endent pathway in mouse heart.
@nl
type
label
Sildenafil induces delayed pre ...... endent pathway in mouse heart.
@en
Sildenafil induces delayed pre ...... endent pathway in mouse heart.
@nl
prefLabel
Sildenafil induces delayed pre ...... endent pathway in mouse heart.
@en
Sildenafil induces delayed pre ...... endent pathway in mouse heart.
@nl
P2093
P1433
P1476
Sildenafil induces delayed pre ...... pendent pathway in mouse heart
@en
P2093
Fadi Salloum
Rakesh C Kukreja
P304
P356
10.1161/01.RES.0000066853.09821.98
P50
P577
2003-03-13T00:00:00Z