Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.
about
Cloning and characterization of LUN, a novel ring finger protein that is highly expressed in lung and specifically binds to a palindromic sequenceBypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locusThe core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progressionmel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activityUSP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2ARING1 is associated with the polycomb group protein complex and acts as a transcriptional repressorIdentification of a polymorphism in the RING finger of human Bmi-1 that causes its degradation by the ubiquitin-proteasome systemThe t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein familyPTEN inhibits BMI1 function independently of its phosphatase activitySeveral distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locusStructure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complexActivation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas.Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrationsControl of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activityStructure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteinsIdentification and preliminary characterization of a protein motif related to the zinc fingerIdentification and characterization of a RING zinc finger gene (C-RZF) expressed in chicken embryo cellsBmi1, stem cells, and senescence regulationThe E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complexbic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNAInteraction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expressionBMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repressionContribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesisUse of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structureA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseTargeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapyEpigenetic plasticity: a central regulator of epithelial-to-mesenchymal transition in cancerHPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression propertiesRing finger in the peroxisome assembly factor-1The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cellsInsertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1The E3 ubiquitin-ligase Bmi1/Ring1A controls the proteasomal degradation of Top2alpha cleavage complex - a potentially new drug targetInk4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.Ubiquitination and degradation of ribonucleotide reductase M1 by the polycomb group proteins RNF2 and Bmi1 and cellular response to gemcitabineDifferential splicing creates a diversity of transcripts from a neurospecific developmentally regulated gene encoding a protein with new zinc-finger motifsTransgenic models of lymphoid neoplasia and development of a pan-hematopoietic vectorGlobal gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancerPolycomb silencers control cell fate, development and cancer
P2860
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P2860
Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
Novel zinc finger gene implica ...... s in E mu-myc transgenic mice.
@en
Novel zinc finger gene implica ...... s in E mu-myc transgenic mice.
@nl
type
label
Novel zinc finger gene implica ...... s in E mu-myc transgenic mice.
@en
Novel zinc finger gene implica ...... s in E mu-myc transgenic mice.
@nl
prefLabel
Novel zinc finger gene implica ...... s in E mu-myc transgenic mice.
@en
Novel zinc finger gene implica ...... s in E mu-myc transgenic mice.
@nl
P2093
P1433
P1476
Novel zinc finger gene implica ...... is in E mu-myc transgenic mice
@en
P2093
S P Klinken
W S Alexander
P304
P356
10.1016/0092-8674(91)90383-A
P407
P577
1991-05-01T00:00:00Z