Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin. - Wikidata - awgldk - TriplyDB

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

http://www.wikidata.org/entity/Q44440242

about

Simultaneous assessment of uptake and metabolism in rat hepatocytes: a comprehensive mechanistic model Basic science review: Statin therapy--Part I: The pleiotropic effects of statins in cardiovascular disease.The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins.Reduced esophageal cancer incidence in statin users, particularly with cyclo-oxygenase inhibition.The effect of rosuvastatin on oestrogen & progestin pharmacokinetics in healthy women taking an oral contraceptive.Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.Rosuvastatin: a highly potent statin for the prevention and management of coronary artery disease.Chronic HMGCR/HMG-CoA reductase inhibitor treatment contributes to dysglycemia by upregulating hepatic gluconeogenesis through autophagy induction Determination of intracellular unbound concentrations and subcellular localization of drugs in rat sandwich-cultured hepatocytes compared with liver tissue.Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes Hepatic basolateral efflux contributes significantly to rosuvastatin disposition II: characterization of hepatic elimination by basolateral, biliary, and metabolic clearance pathways in rat isolated perfused liver.Clinical experience with rosuvastatin in the management of hyperlipidemia and the reduction of cardiovascular risk.Evidence for the efficacy of statins in animal stroke models: a meta-analysis.Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption.Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway.Statin use and uterine fibroid risk in hyperlipidemia patients: a nested case-control study.In vitro biliary clearance of angiotensin II receptor blockers and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in sandwich-cultured rat hepatocytes: comparison with in vivo biliary clearance.Detection of statin cytotoxicity is increased in cells expressing the OATP1B1 transporter.Association between a frequent allele of the gene encoding OATP1B1 and enhanced LDL-lowering response to fluvastatin therapy.Understanding the interplay of drug transporters involved in the disposition of rosuvastatin in the isolated perfused rat liver using a physiologically-based pharmacokinetic model.

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P2860

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

http://www.wikidata.org/entity/Q44440242

description

2003 nî lūn-bûn

@nan

2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-cn

2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

2003年學術文章

@zh-hant

name

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

@en

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

@nl

type

label

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

@en

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

@nl

prefLabel

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

@en

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

@nl

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Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin.

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Higaki K

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Koike M

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P2860

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Future prospects for toxicokinetics: prediction of drug disposition and adverse effects in humans from in vitro measurements of drug metabolism, transport and binding.

Carrier-mediated uptake of pravastatin by rat hepatocytes in primary culture.

Effect of rosuvastatin on low-density lipoprotein cholesterol in patients with hypercholesterolemia.

Pharmacokinetics and disposition of rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in rat.

Liver-specific distribution of rosuvastatin in rats: comparison with pravastatin and simvastatin.

Immunohistochemical distribution and functional characterization of an organic anion transporting polypeptide 2 (oatp2).

Uptake of organic anions by isolated rat hepatocytes. A classification in terms of ATP-dependency.

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