Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling.
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MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activityThe rise of mitochondria in medicineMitochondrial Quality Control and Muscle Mass MaintenanceModulation of the matrix redox signaling by mitochondrial Ca(2.)Calcium signaling as a mediator of cell energy demand and a trigger to cell deathThe regulation of neuronal mitochondrial metabolism by calciumMitochondrial calcium transport in trypanosomesReliance of ER-mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriersThe EF-Hand Ca2+ Binding Protein MICU Choreographs Mitochondrial Ca2+ Dynamics in ArabidopsisWhat is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future researchStructure and function of the mitochondrial calcium uniporter complexLoss of forebrain MTCH2 decreases mitochondria motility and calcium handling and impairs hippocampal-dependent cognitive functions.Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division.ANO10 mutations cause ataxia and coenzyme Q₁₀ deficiencyThe mitochondrial calcium uniporter: mice can live and die without it.The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo.Mitochondrial calcium uniporter MCU supports cytoplasmic Ca2+ oscillations, store-operated Ca2+ entry and Ca2+-dependent gene expression in response to receptor stimulationHepatitis B virus modulates store-operated calcium entry to enhance viral replication in primary hepatocytesCa2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.Mitochondrial Calcium Uptake Modulates Synaptic Vesicle Endocytosis in Central Nerve TerminalsMICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhoodThe mitochondrial Ca2+ uniporter: regulation by auxiliary subunits and signal transduction pathways.The Spectrum of Mitochondrial Ultrastructural Defects in Mitochondrial Myopathy.MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders.Mitochondrial channels: ion fluxes and more.The mitochondrial Ca(2+) uniporter complexDisturbed mitochondrial dynamics and neurodegenerative disorders.Life after the birth of the mitochondrial Na+/Ca2+ exchanger, NCLX.Copy number variation in 19 Italian multiplex families with autism spectrum disorder: Importance of synaptic and neurite elongation genes.Inhibiting the Mitochondrial Calcium Uniporter during Development Impairs Memory in Adult Drosophila.Organization of junctional sarcoplasmic reticulum proteins in skeletal muscle fibers.Regulation of mitochondrial calcium in plants versus animals.The gatekeepers of mitochondrial calcium influx: MICU1 and MICU2Improved skeletal muscle Ca2+ regulation in vivo following contractions in mice overexpressing PGC-1α.Impaired expression of the mitochondrial calcium uniporter suppresses mast cell degranulation.Impact of intracellular ion channels on cancer development and progression.Mitochondrial Ca(2+) uptake in skeletal muscle health and disease.Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging.
P2860
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P2860
Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
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2013年学术文章
@zh-sg
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name
Loss-of-function mutations in ...... tochondrial calcium signaling.
@en
Loss-of-function mutations in ...... tochondrial calcium signaling.
@en-gb
Loss-of-function mutations in ...... tochondrial calcium signaling.
@nl
type
label
Loss-of-function mutations in ...... tochondrial calcium signaling.
@en
Loss-of-function mutations in ...... tochondrial calcium signaling.
@en-gb
Loss-of-function mutations in ...... tochondrial calcium signaling.
@nl
prefLabel
Loss-of-function mutations in ...... tochondrial calcium signaling.
@en
Loss-of-function mutations in ...... tochondrial calcium signaling.
@en-gb
Loss-of-function mutations in ...... tochondrial calcium signaling.
@nl
P2093
P50
P356
P1433
P1476
Loss-of-function mutations in ...... tochondrial calcium signaling.
@en
P2093
A Reghan Foley
Anne-Marie Childs
Caroline A Sewry
Colin A Johnson
Eamonn Sheridan
Francesco Muntoni
Gijs W E Santen
György Szabadkai
Helen Roper
Ieke Ginjaar
P2888
P304
P356
10.1038/NG.2851
P407
P50
P577
2013-12-15T00:00:00Z