Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex.
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S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activitiesArgininosuccinate synthase: at the center of arginine metabolismGut microbiota in alcoholic liver disease: pathogenetic role and therapeutic perspectivesEndothelial caveolar subcellular domain regulation of endothelial nitric oxide synthaseProtein kinase A-dependent translocation of Hsp90 alpha impairs endothelial nitric-oxide synthase activity in high glucose and diabetesMetabolic actions of angiotensin II and insulin: a microvascular endothelial balancing actProtein kinase D interacts with neuronal nitric oxide synthase and phosphorylates the activatory residue serine 1412Endothelial nitric oxide synthase in the microcirculation.GIGANTEA is a co-chaperone which facilitates maturation of ZEITLUPE in the Arabidopsis circadian clockPost-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penisFluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signallingSerum from calorie-restricted rats activates vascular cell eNOS through enhanced insulin signaling mediated by adiponectin.Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage.Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats.(-)-Epicatechin induces calcium and translocation independent eNOS activation in arterial endothelial cells.Chronic activation of AMP-activated protein kinase prevents 20-hydroxyeicosatetraenoic acid-induced endothelial dysfunction.A model in which heat shock protein 90 targets protein-folding clefts: rationale for a new approach to neuroprotective treatment of protein folding diseasesHeme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleftBone morphogenetic protein receptor II is a novel mediator of endothelial nitric-oxide synthase activation.Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in miceDecreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning.The prolactin family hormones regulate vascular tone through NO and prostacyclin production in isolated rat aortic ringsEffects of dietary decosahexaenoic acid (DHA) on eNOS in human coronary artery endothelial cellsModulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitinationSrc-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase.International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].Decreased endothelial nitric oxide synthase expression and function contribute to impaired mitochondrial biogenesis and oxidative stress in fetal lambs with persistent pulmonary hypertension.Recent advances in understanding endothelial dysfunction in atherosclerosis.Subcellular targeting and trafficking of nitric oxide synthases.Endothelial dysfunction in diabetic erectile dysfunction.Hyperglycemia in acute ischemic stroke: a vascular perspective.Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation.Review article: steroid hormones and uterine vascular adaptation to pregnancy.Regulation of the nitric oxide pathway genes by tetrahydrofurandiols: microarray analysis of MCF-7 human breast cancer cells.Mechanisms and consequences of endothelial nitric oxide synthase dysfunction in hypertensionLife history of eNOS: partners and pathways.Renin-angiotensin-aldosterone system and oxidative stress in cardiovascular insulin resistance.SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERKShear-Induced Nitric Oxide Production by Endothelial Cells.Insulin signalling in the heart.
P2860
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P2860
Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Synergistic activation of endo ...... 90-Akt-CaM-bound eNOS complex.
@en
Synergistic activation of endothelial nitric-oxide synthase
@nl
type
label
Synergistic activation of endo ...... 90-Akt-CaM-bound eNOS complex.
@en
Synergistic activation of endothelial nitric-oxide synthase
@nl
prefLabel
Synergistic activation of endo ...... 90-Akt-CaM-bound eNOS complex.
@en
Synergistic activation of endothelial nitric-oxide synthase
@nl
P2860
P356
P1476
Synergistic activation of endo ...... 90-Akt-CaM-bound eNOS complex.
@en
P2093
Michael E Mendelsohn
Satoru Takahashi
P2860
P304
30821-30827
P356
10.1074/JBC.M304471200
P407
P577
2003-06-10T00:00:00Z