Imaging 26S proteasome activity and inhibition in living mice.
about
Proteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4Conserved signal peptide of Notch3 inhibits interaction with proteasomeNoninvasive molecular imaging of c-Myc activation in living miceHistone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibersIn vivo bioluminescent imaging (BLI): noninvasive visualization and interrogation of biological processes in living animalsCharacterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunitThe casein kinase 2-nrf1 axis controls the clearance of ubiquitinated proteins by regulating proteasome gene expressionStressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cellsWhole animal imaging.Molecular imaging: spawning a new melting-pot for biomedical imaging.Real-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells.FGFR1 inhibits skeletal muscle atrophy associated with hindlimb suspensionMicrofluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells.Haematopoietic stem cells require a highly regulated protein synthesis rate.Macroscopic stiffness of breast tumors predicts metastasis.Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways.Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters.Reduction in ATP levels triggers immunoproteasome activation by the 11S (PA28) regulator during early antiviral response mediated by IFNβ in mouse pancreatic β-cells.Molecular imaging in tumor angiogenesis and relevant drug researchTranslational molecular imaging for cancer.In vivo bioluminescence for tracking cell fate and function.α,β-Unsaturated carbonyl system of chalcone-based derivatives is responsible for broad inhibition of proteasomal activity and preferential killing of human papilloma virus (HPV) positive cervical cancer cells.Stem cell transplantation for multiple myeloma.Endothelial CXCR7 regulates breast cancer metastasisRole of reporter gene imaging in molecular and cellular biology.Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells.Optical imaging of tumor cells in hollow fibers: evaluation of the antitumor activities of anticancer drugs and target validationIsolation of Anti-Ricin Protective Antibodies Exhibiting High Affinity from Immunized Non-Human Primates.Integrated protein quality-control pathways regulate free α-globin in murine β-thalassemia.Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymesReal-time imaging of beta-catenin dynamics in cells and living mice.Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazineActivity-based near-infrared fluorescent probe for LMP7: a chemical proteomics tool for the immunoproteasome in living cells.Enhancement of 26S proteasome functionality connects oxidative stress and vascular endothelial inflammatory response in diabetes mellitus.Proteasomal inhibition sensitizes cervical cancer cells to mitomycin C-induced bystander effect: the role of tumor microenvironment.Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells.Improved antibody-based ricin neutralization by affinity maturation is correlated with slower off-rate values.Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice.Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis.In vivo monitoring of CD44+ cancer stem-like cells by γ-irradiation in breast cancer.
P2860
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P2860
Imaging 26S proteasome activity and inhibition in living mice.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Imaging 26S proteasome activity and inhibition in living mice.
@en
Imaging 26S proteasome activity and inhibition in living mice.
@nl
type
label
Imaging 26S proteasome activity and inhibition in living mice.
@en
Imaging 26S proteasome activity and inhibition in living mice.
@nl
prefLabel
Imaging 26S proteasome activity and inhibition in living mice.
@en
Imaging 26S proteasome activity and inhibition in living mice.
@nl
P2093
P356
P1433
P1476
Imaging 26S proteasome activity and inhibition in living mice.
@en
P2093
Christina M Pica
David Piwnica-Worms
Gary D Luker
Jiling Song
P2888
P304
P356
10.1038/NM894
P407
P577
2003-07-01T00:00:00Z
P5875
P6179
1021570797