Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter.
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Diurnal difference in CAR mRNA expressionUp-Regulation of CYP2C19 Expression by BuChang NaoXinTong via PXR Activation in HepG2 CellsThe transcriptional regulation of the human CYP2C genesGlobal gene expression analysis in the livers of rat offspring perinatally exposed to low doses of 2,2',4,4'-tetrabromodiphenyl ether.Clinical application of transcriptional activators of bile salt transporters.Hepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytesRetinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3).CAR2 displays unique ligand binding and RXRalpha heterodimerization characteristics.The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver.Voriconazole plasma concentrations in immunocompromised pediatric patients vary by CYP2C19 diplotypes.Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.Med25 is required for estrogen receptor alpha (ERα)-mediated regulation of human CYP2C9 expression.A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression.Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells.Phenytoin induction of the cyp2c37 gene is mediated by the constitutive androstane receptor.Small-molecule modulators of the constitutive androstane receptor.Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19.Cross-talk between xenobiotic detoxication and other signalling pathways: clinical and toxicological consequences.Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring.Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liverThe influence of combination use of CYP450 inducers on the pharmacokinetics of voriconazole: a systematic review.Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19.Luminogenic cytochrome P450 assays.Role of CAR and PXR in xenobiotic sensing and metabolism.Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.A retrospective analysis of patient-specific factors on voriconazole clearance.Induction of CYP2C19 and CYP3A activity following repeated administration of efavirenz in healthy volunteers.Pharmacokinetic drug interaction profile of omeprazole with adverse consequences and clinical risk management.Antiproliferation of berberine is mediated by epigenetic modification of constitutive androstane receptor (CAR) metabolic pathway in hepatoma cells.Regulatory polymorphisms in CYP2C19 affecting hepatic expressionIdentification of human CYP2C8 as a retinoid-related orphan nuclear receptor target gene.Phenobarbital elicits unique, early changes in the expression of hepatic genes that affect critical pathways in tumor-prone B6C3F1 mice.The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumorsRegulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids.Methods for the quantitative evaluation and prediction of CYP enzyme induction using human in vitro systems.Induction of cytochrome P450 enzymes: a view on human in vivo findings.Nuclear receptors in the cross-talk of drug metabolism and inflammation.Cytochrome P450 enzyme regulation by glucocorticoids and consequences in terms of drug interaction.Nuclear hormone receptors PXR and CAR and metabolic diseases.
P2860
Q24792012-FD8C25DE-CA36-474E-BB43-91038CFF8741Q28553219-55FE93DC-7F7F-4BE2-9666-DE9EF78A6F66Q33597311-DBCE4A89-FE25-4270-A9B4-D95272B8631EQ33702926-DE25A780-ED0D-4C59-848D-58A05F37AFF9Q33709930-888E14ED-204A-4A6F-A7AF-0267214109B8Q33754808-77F1A0A9-AE0F-41D6-B12B-C46D811F8AF3Q33781766-11C4256B-AEBD-476A-8D89-2F19218BF2FCQ33926322-B3D7A8A9-5918-4999-8BCE-D7ACA2F2C1DEQ34015661-427753F7-254D-4A07-BC59-C6089EA8B02DQ34138276-AF8BC605-7888-4810-8AB1-CB248DC2CAD5Q34349336-F3779136-4469-4B79-A8AE-7F4C2086ACF9Q34938770-122925E9-D219-4CF5-A06C-EEA8D880E940Q34987539-5A2A6168-23CD-4EE5-A09F-6E806AC4C347Q35129013-F4561F45-1C6C-42EF-B0EA-3B7B6453873DQ35185572-B5E75436-8338-4A89-B1F8-8912116406ADQ35748820-50DCBD34-8B86-420D-BCDE-9A9377523DD9Q35919726-906A4F5E-8461-4CF4-BA32-373E17F180B2Q35952367-13052906-101F-46F8-ABD8-52B1DA639794Q36020962-A43B0703-4FC6-4705-A602-C4151F40D975Q36172497-D20542A7-EDAD-4280-A285-44A12622C22DQ36174736-67AD90BF-1875-4798-AFA6-2DF6ECF16883Q36273788-9C21206B-7A0B-49D5-A1E4-361BC8651DB7Q36307008-E279269B-A533-4CC6-BE87-FE411F954068Q36543124-1CE52E96-8820-4CB4-A475-2F24884E6B79Q36672089-6BA4D757-BA56-4E0C-98D3-B8593214ABCDQ36795136-53DA5149-8903-4B07-B483-7B7CC0AB4973Q36810454-25E0010F-030C-4CD9-AE0D-33B7BC8E8F81Q36887128-15255B6F-1B0C-4124-9ACD-73BE0971B03AQ36900535-43CF1DC0-4494-4CAF-BF2A-9B488C33E270Q37014980-4DD94975-407C-4EAA-89C5-B63A39BE8EA0Q37127419-C145FA21-50FE-421B-9A8D-EB87F185EEC5Q37162165-F6C1978A-B772-4E00-AB55-5BB11CB51CD7Q37196691-1814CD89-8584-4AD1-90D7-3C3F04FA3ED8Q37256627-6FBFCDE3-8905-403F-885F-D005EBB7C666Q37756178-52428937-66D6-4EE9-9679-784F6FD6F888Q38028549-352C7364-F61F-4C62-9744-D875E4819325Q38057372-230F42C5-BE95-48BF-B246-1A36936D53F8Q38074993-A3CCC1A1-FAC5-4FB3-B1E7-DA7718266F27Q38180822-80826039-D6CC-435C-8E04-3ABB08B77A70Q38267499-8ED2D9BF-32D7-4134-9423-C76B94D03DC4
P2860
Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Identification of constitutive ...... sites in the CYP2C19 promoter.
@en
Identification of constitutive ...... sites in the CYP2C19 promoter.
@nl
type
label
Identification of constitutive ...... sites in the CYP2C19 promoter.
@en
Identification of constitutive ...... sites in the CYP2C19 promoter.
@nl
prefLabel
Identification of constitutive ...... sites in the CYP2C19 promoter.
@en
Identification of constitutive ...... sites in the CYP2C19 promoter.
@nl
P2093
P356
P1476
Identification of constitutive ...... sites in the CYP2C19 promoter.
@en
P2093
Joyce A Goldstein
Masahiko Negishi
Stephen S Ferguson
Yuping Chen
P304
P356
10.1124/MOL.64.2.316
P577
2003-08-01T00:00:00Z