Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice.
about
Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'Residual platelet ADP reactivity after clopidogrel treatment is dependent on activation of both the unblocked P2Y(1) and the P2Y (12) receptor and is correlated with protein expression of P2Y (12)Platelets in atherothrombosis: lessons from mouse models.Platelet receptors and signaling in the dynamics of thrombus formation.Platelet receptor signaling in thrombus formation.Adenosine and blood platelets.Calmodulin interacts with the platelet ADP receptor P2Y1Conditional overexpression of transgenes in megakaryocytes and platelets in vivo.Discontinuation of long term clopidogrel therapy induces platelet rebound hyperaggregability between 2 and 6 weeks post cessation.Dual P2Y 12 receptor signaling in thrombin-stimulated platelets--involvement of phosphoinositide 3-kinase beta but not gamma isoform in Ca2+ mobilization and procoagulant activity.Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity.
P2860
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P2860
Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice.
description
2003 nî lūn-bûn
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2003年の論文
@ja
2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
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2003年学术文章
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2003年學術文章
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2003年學術文章
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name
Lineage-specific overexpressio ...... reactivity in transgenic mice.
@en
Lineage-specific overexpressio ...... reactivity in transgenic mice.
@nl
type
label
Lineage-specific overexpressio ...... reactivity in transgenic mice.
@en
Lineage-specific overexpressio ...... reactivity in transgenic mice.
@nl
prefLabel
Lineage-specific overexpressio ...... reactivity in transgenic mice.
@en
Lineage-specific overexpressio ...... reactivity in transgenic mice.
@nl
P2093
P2860
P1476
Lineage-specific overexpressio ...... -reactivity in transgenic mice
@en
P2093
P2860
P304
P356
10.1046/J.1538-7836.2003.00003.X
P577
2003-01-01T00:00:00Z