Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases.
about
Composition and histone substrates of polycomb repressive group complexes change during cellular differentiationLoss of NKX3.1 favors vascular endothelial growth factor-C expression in prostate cancerGenome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cellsA network biology approach to prostate cancerPten dose dictates cancer progression in the prostateMouse Models in Prostate Cancer Translational Research: From Xenograft to PDXGenetically engineered mouse models of prostate cancerGenetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse modelsKLF5 inhibits angiogenesis in PTEN-deficient prostate cancer by attenuating AKT activation and subsequent HIF1α accumulationId4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTENAdditive Effect of Zfhx3/Atbf1 and Pten Deletion on Mouse Prostatic TumorigenesisThe Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathwaysThe effects of aging on the molecular and cellular composition of the prostate microenvironment.Loss of the SSeCKS/Gravin/AKAP12 gene results in prostatic hyperplasiaInterleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment.TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.Mouse models of prostate cancer: picking the best model for the question.Tumor-suppressive functions of 15-Lipoxygenase-2 and RB1CC1 in prostate cancerNKX3.1 as a marker of prostatic origin in metastatic tumors.Molecular genetics of prostate cancer: new prospects for old challengesDietary energy balance modulates prostate cancer progression in Hi-Myc miceThe PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Molecular pathways and targets in prostate cancerEpigenetics of prostate cancer: beyond DNA methylationKlf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathwaysNKX3.1 is regulated by protein kinase CK2 in prostate tumor cellsCooperation between Stat3 and Akt signaling leads to prostate tumor development in transgenic mice.Concomitant loss of EAF2/U19 and Pten synergistically promotes prostate carcinogenesis in the mouse model.Integrating differentiation and cancer: the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis.Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma.Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer.Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: the FLiMP mouse model.Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism.Persistent inflammation leads to proliferative neoplasia and loss of smooth muscle cells in a prostate tumor modelHER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancerFrequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.TNFα-mediated loss of β-catenin/E-cadherin association and subsequent increase in cell migration is partially restored by NKX3.1 expression in prostate cellsInteraction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression.Animal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells.
P2860
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P2860
Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
Nkx3.1; Pten mutant mice devel ...... oma and lymph node metastases.
@en
Nkx3.1; Pten mutant mice devel ...... oma and lymph node metastases.
@nl
type
label
Nkx3.1; Pten mutant mice devel ...... oma and lymph node metastases.
@en
Nkx3.1; Pten mutant mice devel ...... oma and lymph node metastases.
@nl
prefLabel
Nkx3.1; Pten mutant mice devel ...... oma and lymph node metastases.
@en
Nkx3.1; Pten mutant mice devel ...... oma and lymph node metastases.
@nl
P2093
P1433
P1476
Nkx3.1; Pten mutant mice devel ...... oma and lymph node metastases.
@en
P2093
Alexander D Borowsky
Cory Abate-Shen
Jeffery P Gregg
Kyriakos D Economides
Nishita Desai
Robert D Cardiff
Whitney A Banach-Petrosky
Xiaohui Sun
P304
P407
P577
2003-07-01T00:00:00Z