Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer. - Wikidata - awgldk - TriplyDB

Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer.

Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer.

http://www.wikidata.org/entity/Q35080706

about

Dietary flavonoid fisetin: a novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice Pterostilbene-isothiocyanate conjugate suppresses growth of prostate cancer cells irrespective of androgen receptor status Additive Effect of Zfhx3/Atbf1 and Pten Deletion on Mouse Prostatic Tumorigenesis Deletion of atbf1/zfhx3 in mouse prostate causes neoplastic lesions, likely by attenuation of membrane and secretory proteins and multiple signaling pathways.Transcriptional activity of c-Jun is critical for the suppression of AR function.The current state of preclinical prostate cancer animal models.BRAF activation initiates but does not maintain invasive prostate adenocarcinoma Analysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems.Endothelial cell-derived interleukin-6 regulates tumor growth.Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing.TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.The tumor suppressive role of CAMK2N1 in castration-resistant prostate cancer.Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor Molecular genetics of prostate cancer: new prospects for old challenges SPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene.Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population.Molecular pathways and targets in prostate cancer Sprouty genes function in suppression of prostate tumorigenesis Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.Eupafolin suppresses prostate cancer by targeting phosphatidylinositol 3-kinase-mediated Akt signaling.Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice.CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling.Integrating differentiation and cancer: the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis.Conditional expression of the androgen receptor induces oncogenic transformation of the mouse prostate.BRAF Mutations in Canine Cancers.Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer.Combined AKT and MEK Pathway Blockade in Pre-Clinical Models of Enzalutamide-Resistant Prostate Cancer.Activating BRAF gene mutations are uncommon in hormone refractory prostate cancer in Caucasian patients B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer Androgen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice.Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention.Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implications Targeting the androgen receptor pathway in prostate cancer.AKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion.Portrait of PTEN: messages from mutant mice.The immunophilin ligands cyclosporin A and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanisms Effects of manganese superoxide dismutase silencing on androgen receptor function and gene regulation: implications for castration-resistant prostate cancer

P2860

Q27026839-6062155D-99EE-4396-8E1C-498C5C3B2BCD Q28533254-8F7F9C78-A201-4EA0-B0B4-A808E3429057 Q28541923-9D4DDB4E-2A10-4F1D-A469-B7FC15F70770 Q30278925-77781374-052E-4083-ADBE-B13A63A42FBE Q30410016-07267EAD-7E47-44EA-861A-B2F9781C86C3 Q30412500-EB2783A4-A784-4B68-8CBE-4619467CCB90 Q30418797-F08F3AAA-68B4-4051-B4FB-96924C151779 Q33392719-7613441B-4211-448F-A1D3-B9E437A66B86 Q33529070-23844D43-9ED4-48EA-A151-DBF0ED7B3D78 Q33592677-E408D0FC-7D0A-4DBA-BAF1-08B4F8A7D8AB Q33687282-264CDC7E-5D7E-4F16-B780-3D5B603E7EF0 Q33770060-41270DC4-C7BA-40B8-B18F-1CD3D42F1140 Q33803841-EADF1EB7-4F75-448A-A51C-6E3D9ED2991E Q33976977-BBC8B5D2-85B4-4F13-9E33-986FA008E20E Q34097585-3169E980-8EF6-42C3-B079-67D44FA3D7D0 Q34127462-CFDA6D9A-9087-44B2-85CA-D98457F485F0 Q34257025-CA84B224-0A1B-4A10-850F-4331A790A3B7 Q34345248-8F6F15C7-31AB-43F5-BBDF-9FA9BBF0CBE4 Q34365632-7352D8C2-03B0-495F-82EA-561F94D32A10 Q34476381-E5890B6A-89B2-42C7-9191-58DA7BDBC423 Q34545106-35362DAE-5CB4-4056-A626-C578BDC5487E Q34566607-09FB886A-F301-4239-9DF8-160335EC5B73 Q34724225-68810948-126D-4355-8CB5-D55695F259E9 Q34786431-4E00C036-49C5-4A25-BCA0-32B13802AC8C Q34786771-519C8140-24A0-4043-A06B-93CE8C16F128 Q35312172-A75FCEF5-DADB-48DA-9678-C953A9A68F3A Q35656395-77647C7A-35BB-4DDA-99BE-38659411074E Q35723937-B7A232A9-5812-47BB-A25C-58654B6E543D Q35980053-E6CF5E53-E808-49AE-9DD7-224376F695E4 Q36216904-572A418F-6268-447A-9832-2FC5B1CF2C05 Q36243554-2443C5BE-4515-4F03-98A5-17494968EB8B Q36355602-8BAAC67D-76DE-44B7-A606-EDE841DD247E Q36536821-1997BC17-290F-476B-8B1B-8544F415262D Q36841356-99E38C67-7FB7-4870-B445-39550A649641 Q36892504-CCE5F30C-1FC4-4B5D-A9E5-7753734650B8 Q36953028-4BC8725C-F744-48C8-A1A2-4B4FBB912ADA Q36977833-EF650104-26E3-40DA-9AED-83984286F94E Q37059129-6E936AB3-86D3-42F5-9363-0CA5CDD8F112 Q37091570-5463DC75-07F7-4C36-9500-7C9F449ED410 Q37162112-BC740DC9-923A-4F02-8F90-A088D12BC381

P2860

Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer.

http://www.wikidata.org/entity/Q35080706

description

2006 nî lūn-bûn

@nan

2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Combinatorial activities of Ak ...... n-independent prostate cancer.

@ast

Combinatorial activities of Ak ...... n-independent prostate cancer.

@en

type

label

Combinatorial activities of Ak ...... n-independent prostate cancer.

@ast

Combinatorial activities of Ak ...... n-independent prostate cancer.

@en

prefLabel

Combinatorial activities of Ak ...... n-independent prostate cancer.

@ast

Combinatorial activities of Ak ...... n-independent prostate cancer.

@en

P1433

Q35080706-C9A7C2F4-7D9B-459F-82E3-2331A169B64E

P1476

Q35080706-812F4A77-0C87-4602-961F-91961433FFC8

P2093

Q35080706-16A40A38-6F0D-4D03-9987-71974962A899

Q35080706-1DF6A50C-8860-457E-89F6-3C09B751519A

Q35080706-3B68D3A1-AE60-4623-8C20-726B454B8EF9

Q35080706-4DE5D490-6A75-4764-804B-D81DD0A11A85

Q35080706-81FE1788-95C5-4E5B-A5E7-BAC62E827804

Q35080706-E65263A8-2BEE-4D94-9E06-E24F8967797E

P2860

Q35080706-0033269B-B819-4F35-B212-9314EC22ECBB

Q35080706-09770867-ACA8-4A0B-A54B-FA6DF76A77F0

Q35080706-199A8690-1AB8-47A7-BDCB-E25DB021964E

Q35080706-1DC9F8F9-72E2-497B-8F48-7E12CCD45072

Q35080706-216C0125-FBAE-4707-AEBB-360C09FD920C

Q35080706-3A008202-0081-416C-AAC9-F6BA1EF0C780

Q35080706-5575F08D-3452-44A4-BA07-C2F1A335319B

Q35080706-577A406D-9082-4349-9471-0132BAC992B0

Q35080706-5D92FF6C-3771-4101-8166-E46270AEC69B

Q35080706-6570A4FA-CC0D-459E-A79B-59DF2EE89A2F

P304

Q35080706-172E2B53-B3C0-42F7-BF3F-FB4033AB5E85

P31

Q35080706-B11B8C0B-FEE2-40ED-91FD-D5CB8E8062F7

P356

Q35080706-1967E894-BDAC-4114-8FE4-BFB6B4E629A7

P407

Q35080706-B0A1820F-152F-4FD4-9266-A7FBA46B9BB3

P433

Q35080706-0BE49532-6F73-458F-B845-EECC84EEA6D1

P478

Q35080706-D193A22D-0B95-41C3-B8D7-F9A706AB4A9C

P577

Q35080706-B758DFAB-AAB6-49EF-8181-8F715DB971FB

P5875

Q35080706-6F6174C4-E5A7-472D-98E2-62F7B74274FD

P698

Q35080706-BDAF2E7F-AF2F-4138-A475-2F7DE5FDDE18

P932

Q35080706-485A1C5C-F1B0-4759-91D7-09BDC652FAD6

P356

PNAS.0606836103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Combinatorial activities of Ak ...... n-independent prostate cancer.

@en

P2093

Cory Abate-Shen

http://www.w3.org/2001/XMLSchema#string

Hui Gao

http://www.w3.org/2001/XMLSchema#string

Michael M Shen

http://www.w3.org/2001/XMLSchema#string

Whitney A Banach-Petrosky

http://www.w3.org/2001/XMLSchema#string

William L Gerald

http://www.w3.org/2001/XMLSchema#string

Xuesong Ouyang

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations of the BRAF gene in human cancer

Molecular determinants of resistance to antiandrogen therapy

Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium

Roles for Nkx3.1 in prostate development and cancer

Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

The development of androgen-independent prostate cancer

Androgen receptor in prostate cancer

Chromosomal deletions and tumor suppressor genes in prostate cancer.

P304

14477-14482

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0606836103

http://www.w3.org/2001/XMLSchema#string

P407

P433

39

http://www.w3.org/2001/XMLSchema#string

P478

103

http://www.w3.org/2001/XMLSchema#string

P577

2006-09-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6817127

http://www.w3.org/2001/XMLSchema#string

P698

16973750

http://www.w3.org/2001/XMLSchema#string

P932

1599986

http://www.w3.org/2001/XMLSchema#string