Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.
about
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradationLRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergyVertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis.Notch and Egfr signaling act antagonistically to regulate germ-line stem cell niche formation in Drosophila male embryonic gonadsThe leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases.gone early, a novel germline factor, ensures the proper size of the stem cell precursor pool in the Drosophila ovary.Conservation of an inhibitor of the epidermal growth factor receptor, Kekkon1, in dipteransKnockouts of Kekkon1 define sequence elements essential for Drosophila epidermal growth factor receptor inhibition.Bipartite inhibition of Drosophila epidermal growth factor receptor by the extracellular and transmembrane domains of Kekkon1.Negative regulation of ErbB family receptor tyrosine kinasesRegulation of the BMP Signaling-Responsive Transcriptional Network in the Drosophila Embryo.Immunoglobulin superfamily members play an important role in the mosquito immune systemMechanisms of ErbB receptor negative regulation and relevance in cancer.Feedback control of the EGFR signaling gradient: superposition of domain-splitting events in Drosophila oogenesis.New insights into the control of neurotrophic growth factor receptor signaling: implications for nervous system development and repair.Regulatory mechanisms of EGFR signalling during Drosophila eye development.LRIG1, a candidate tumour-suppressor gene in human bladder cancer cell line BIU87.Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons.A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity.Control of bract formation in Drosophila: poxn, kek1, and the EGF-R pathway.Conserved cross-interactions in Drosophila and Xenopus between Ras/MAPK signaling and the dual-specificity phosphatase MKP3.Determination in oocytes of the reproductive modes for the brine shrimp Artemia parthenogenetica.
P2860
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P2860
Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.
description
2003 nî lūn-bûn
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name
Mechanism of inhibition of the ...... ransmembrane protein Kekkon 1.
@en
Mechanism of inhibition of the ...... ransmembrane protein Kekkon 1.
@nl
type
label
Mechanism of inhibition of the ...... ransmembrane protein Kekkon 1.
@en
Mechanism of inhibition of the ...... ransmembrane protein Kekkon 1.
@nl
prefLabel
Mechanism of inhibition of the ...... ransmembrane protein Kekkon 1.
@en
Mechanism of inhibition of the ...... ransmembrane protein Kekkon 1.
@nl
P2093
P356
P1433
P1476
Mechanism of inhibition of the ...... transmembrane protein Kekkon 1
@en
P2093
Christian Ghiglione
David Bilder
John A Diamonti
Kermit L Carraway III
Margret Andresdottir
Norbert Perrimon
P304
P356
10.1242/DEV.00617
P407
P577
2003-09-01T00:00:00Z