Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells.
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In vivo CD8+ T cell dynamics in the liver of Plasmodium yoelii immunized and infected miceProlonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasitesIdentification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite ProteinProtective immunity to liver-stage malariaEffector memory Th1 CD4 T cells are maintained in a mouse model of chronic malariaMacrophage and T cell dynamics during the development and disintegration of mycobacterial granulomasImmunization with radiation-attenuated Plasmodium berghei sporozoites induces liver cCD8alpha+DC that activate CD8+T cells against liver-stage malaria.Phenotypic characterization of Plasmodium berghei responsive CD8+ T cells after immunization with live sporozoites under chloroquine coverExtreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites.Engineering of Genetically Arrested Parasites (GAPs) For a Precision Malaria VaccineInvariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice.Artesunate versus chloroquine infection-treatment-vaccination defines stage-specific immune responses associated with prolonged sterile protection against both pre-erythrocytic and erythrocytic Plasmodium yoelii infection.Advances and challenges in malaria vaccine development.Long term protection after immunization with P. berghei sporozoites correlates with sustained IFNγ responses of hepatic CD8+ memory T cells.A nonintegrative lentiviral vector-based vaccine provides long-term sterile protection against malariaA phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS.CD8+ T-cell memory in tumor immunology and immunotherapy.Cutting edge: attrition of Plasmodium-specific memory CD8 T cells results in decreased protection that is rescued by booster immunization.Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasitesAntigen-specific CD8+ T cells and the development of central memory during Mycobacterium tuberculosis infection.Early transcriptional responses of HepG2-A16 liver cells to infection by Plasmodium falciparum sporozoitesStudying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malariaImmunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8+ T cell response in the liverMurine immune responses to liver-stage antigen 1 protein FMP011, a malaria vaccine candidate, delivered with adjuvant AS01B or AS02AComparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates.Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cellsCD8+ T effector memory cells protect against liver-stage malaria.Non-malignant clonal expansions of CD8+ memory T cells in aged individuals.Malaria vaccines in development.Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cellsProtective and pathogenic roles of CD8+ T cells during malaria infection.Differential contributions of central and effector memory T cells to recall responses.Pre-erythrocytic malaria vaccines: towards greater efficacy.Memory CD8 T cells specific for plasmodia liver-stage antigens maintain protracted protection against malaria.Cross-species immunity in malaria vaccine development: two, three, or even four for the price of one?Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron AGenetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells.Genetically engineered, attenuated whole-cell vaccine approaches for malaria.The survival of memory CD8 T cells that is mediated by IL-15 correlates with sustained protection against malaria.Polymeric linear Peptide chimeric vaccine-induced antimalaria immunity is associated with enhanced in vitro antigen loading
P2860
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P2860
Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Protracted protection to Plasm ...... ous liver memory CD8+ T cells.
@en
Protracted protection to Plasm ...... ous liver memory CD8+ T cells.
@nl
type
label
Protracted protection to Plasm ...... ous liver memory CD8+ T cells.
@en
Protracted protection to Plasm ...... ous liver memory CD8+ T cells.
@nl
prefLabel
Protracted protection to Plasm ...... ous liver memory CD8+ T cells.
@en
Protracted protection to Plasm ...... ous liver memory CD8+ T cells.
@nl
P2093
P1476
Protracted protection to Plasm ...... ous liver memory CD8+ T cells.
@en
P2093
Dmitri Berenzon
Jackie Williams
Lisa Letellier
Mimi Guebre-Xabier
Robert J Schwenk
Urszula Krzych
P304
P356
10.4049/JIMMUNOL.171.4.2024
P407
P577
2003-08-01T00:00:00Z