Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase.
about
Acyltransferase mediated polyketide release from a fungal megasynthaseThe enzymology of combinatorial biosynthesis.Isolation and characterisation of the epothilone gene cluster with flanks from high alkalotolerant strain Sorangium cellulosum (So0157-2).Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptidesThe type I fatty acid and polyketide synthases: a tale of two megasynthasesStructural insights into nonribosomal peptide enzymatic assembly linesPKS and NRPS release mechanisms.Frontiers and opportunities in chemoenzymatic synthesis.Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin.Macrodiolide Formation by the Thioesterase of a Modular Polyketide Synthase.A thioesterase from an iterative fungal polyketide synthase shows macrocyclization and cross coupling activity and may play a role in controlling iterative cycling through product offloading.A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst.Macrodiolide formation by the thioesterase of a modular polyketide synthase.
P2860
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P2860
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Epothilone C macrolactonizatio ...... pothilone polyketide synthase.
@en
Epothilone C macrolactonizatio ...... pothilone polyketide synthase.
@nl
type
label
Epothilone C macrolactonizatio ...... pothilone polyketide synthase.
@en
Epothilone C macrolactonizatio ...... pothilone polyketide synthase.
@nl
prefLabel
Epothilone C macrolactonizatio ...... pothilone polyketide synthase.
@en
Epothilone C macrolactonizatio ...... pothilone polyketide synthase.
@nl
P2093
P356
P1476
Epothilone C macrolactonizatio ...... pothilone polyketide synthase.
@en
P2093
Chaitan Khosla
Christopher T Walsh
Kinya Hotta
Tanya L Schneider
P304
P356
10.1021/JA0298646
P407
P577
2003-03-01T00:00:00Z