Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms.
about
Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D3 receptorStereochemical and neuroanatomical selectivity of pramipexole effects on sensorimotor gating in ratsDopamine receptor activation promotes adult neurogenesis in an acute Parkinson modelDevelopment and validation of GC/MS method for determination of pramipexole in rat plasma.Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models.Dopamine receptors and Parkinson's diseaseInteraction of D₃ preferring agonist (-)-N⁶-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (D-264) with cloned human D₂L, D₂S, and D₃ receptors: potent stimulation of mitogen-activated protein kinComputational models of neuronal biophysics and the characterization of potential neuropharmacological targets.D-512 and D-440 as novel multifunctional dopamine agonists: characterization of neuroprotection properties and evaluation of in vivo efficacy in a Parkinson's disease animal modelAdvances and challenges in the search for D2 and D3 dopamine receptor-selective compounds.Neuroprotective arylpiperazine dopaminergic/serotonergic ligands suppress experimental autoimmune encephalomyelitis in rats.Arylpiperazine dopamineric ligands protect neuroblastoma cells from nitric oxide (NO)-induced mitochondrial damage and apoptosis.Neuroprotection by Exendin-4 Is GLP-1 Receptor Specific but DA D3 Receptor Dependent, Causing Altered BrdU Incorporation in Subventricular Zone and Substantia Nigra.Pramipexole has ameliorating effects on levodopa-induced abnormal dopamine turnover in parkinsonian striatum and quenching effects on dopamine-semiquinone generated in vitro.Reassessment of subacute MPTP-treated mice as animal model of Parkinson's disease.Unexpected Neuroprotective Effects of Loganin on 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Neurotoxicity and Cell Death in Zebrafish.
P2860
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P2860
Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Pramipexole inhibits MPTP toxi ...... nt and independent mechanisms.
@en
Pramipexole inhibits MPTP toxi ...... nt and independent mechanisms.
@nl
type
label
Pramipexole inhibits MPTP toxi ...... nt and independent mechanisms.
@en
Pramipexole inhibits MPTP toxi ...... nt and independent mechanisms.
@nl
prefLabel
Pramipexole inhibits MPTP toxi ...... nt and independent mechanisms.
@en
Pramipexole inhibits MPTP toxi ...... nt and independent mechanisms.
@nl
P1476
Pramipexole inhibits MPTP toxi ...... nt and independent mechanisms.
@en
P2093
Andres D Ramirez
Stephen K-F Wong
P356
10.1016/S0014-2999(03)02087-9
P407
P577
2003-08-01T00:00:00Z