A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro.
about
Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokineCardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complexStructural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cellsDiscovery and characterization of olokizumabGraves' ophthalmopathyHistological staining methods preparatory to laser capture microdissection significantly affect the integrity of the cellular RNA.Selective bone marrow involvement of lymphoplasmacytic cells secreting monoclonal IgA rheumatoid factor in a patient with Sjögren's syndrome and serum hyperviscosityMultiple biological activities are expressed by a mouse interleukin 6 cDNA clone isolated from bone marrow stromal cells.Growth inhibition of human breast carcinoma and leukemia/lymphoma cell lines by recombinant interferon-beta 2Anti-nuclear antibody production and immune-complex glomerulonephritis in BALB/c mice treated with pristane.An E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene.IL-6 transgenic mouse model for extraosseous plasmacytoma.The myelin basic protein gene is expressed in differentiated blood cell lineages and in hemopoietic progenitors.p16 INK4a gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB.Interleukin-6 antisense oligonucleotides inhibit the growth of human myeloma cell lines.Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi miceDysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.A computational profiling of changes in gene expression and transcription factors induced by vFLIP K13 in primary effusion lymphomaSelf DNA from lymphocytes that have undergone activation-induced cell death enhances murine B cell proliferation and antibody production.IgG1 plasmacytosis in interleukin 6 transgenic mice.Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cellsFrap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor geneInterleukin-6 and new strategies for the treatment of cancer, hyperproliferative diseases and paraneoplastic syndromes.Secretory products of macrophages.T cells induce terminal differentiation of transformed B cells to mature plasma cell tumors.A granulocyte inhibitory protein overexpressed in chronic renal disease regulates expression of interleukin 6 and interleukin 8.Immunopathogenesis of environmentally induced lupus in mice.Constitutive NF-kappaB activation confers interleukin 6 (IL6) independence and resistance to dexamethasone and Janus kinase inhibitor INCB018424 in murine plasmacytoma cells.Bone marrow microenvironment and the progression of multiple myeloma.Defective development of pristane-oil-induced plasmacytomas in interleukin-6-deficient BALB/c mice.Pristane-induced arthritis in rats: a new model for rheumatoid arthritis with a chronic disease course influenced by both major histocompatibility complex and non-major histocompatibility complex genesBiologic and immunohistochemical analysis of interleukin-6 expression in vivo. Constitutive and induced expression in murine polymorphonuclear and mononuclear phagocytes.Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.In vitro culture of primary plasmacytomas requires stromal cell feeder layers.Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms.Interleukin-HP1, a T cell-derived hybridoma growth factor that supports the in vitro growth of murine plasmacytomas.Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factorMouse plasmacytoma growth in vivo: enhancement by interleukin 6 (IL-6) and inhibition by antibodies directed against IL-6 or its receptor.T cell growth and differentiation induced by interleukin-HP1/IL-6, the murine hybridoma/plasmacytoma growth factor.Oncostatin M, leukemia inhibitory factor, and interleukin 6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130.
P2860
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P2860
A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh-hant
name
A macrophage-derived factor re ...... al and proliferation in vitro.
@en
A macrophage-derived factor re ...... al and proliferation in vitro.
@nl
type
label
A macrophage-derived factor re ...... al and proliferation in vitro.
@en
A macrophage-derived factor re ...... al and proliferation in vitro.
@nl
prefLabel
A macrophage-derived factor re ...... al and proliferation in vitro.
@en
A macrophage-derived factor re ...... al and proliferation in vitro.
@nl
P4510
P356
P1433
P1476
A macrophage-derived factor re ...... al and proliferation in vitro.
@en
P2093
P304
P356
10.1126/SCIENCE.3726549
P407
P577
1986-08-01T00:00:00Z