Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells
about
Hematopoietic stem cell gene therapy:assessing the relevance of preclinical modelsTransplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus.Ex vivo expansion of human hematopoietic stem cells: implications for the modern blood bank.Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.Future prospects for treatment of hemoglobinopathies.Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses.Long-term expression of a T-cell receptor beta-chain gene in mice reconstituted with retrovirus-infected hematopoietic stem cells.Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures.Correction of glucocerebrosidase deficiency after retroviral-mediated gene transfer into hematopoietic progenitor cells from patients with Gaucher disease.Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.Production of human glucocerebrosidase in mice after retroviral gene transfer into multipotential hematopoietic progenitor cells.Long-term in vivo expression of the human glucocerebrosidase gene in nonhuman primates after CD34+ hematopoietic cell transduction with cell-free retroviral vector preparations.Globin gene transfer for the treatment of severe hemoglobinopathies: a paradigm for stem cell-based gene therapy.Gene therapy to protect haematopoietic cells from cytotoxic cancer drugs.Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation.Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cellsProlonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cellsIdentification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia.A chromatin insulator protects retrovirus vectors from chromosomal position effects.Molecular mechanism of transforming growth factor beta-mediated cell-cycle modulation in primary human CD34(+) progenitors.Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow.Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells.Adeno-associated virus type 2-mediated transduction in primary human bone marrow-derived CD34+ hematopoietic progenitor cells: donor variation and correlation of transgene expression with cellular differentiation.Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivoHuman cord blood cells as targets for gene transfer: potential use in genetic therapies of severe combined immunodeficiency disease.Proliferation of totipotent hematopoietic stem cells in vitro with retention of long-term competitive in vivo reconstituting abilityHematologic disease induced in BALB/c mice by a bcr-abl retrovirus is influenced by the infection conditions.Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vectorTransfer and expression of the human multiple drug resistance gene into live miceImproved retroviral gene transfer into murine and Rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor.Long-term expression of gamma-globin mRNA in mouse erythrocytes from retrovirus vectors containing the human gamma-globin gene fused to the ankyrin-1 promoter.The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction.Thrombopoietic potential and serial repopulating ability of murine hematopoietic stem cells constitutively expressing interleukin 11.Direct and synergistic effects of interleukin 11 on murine hemopoiesis in cultureCombination of cytokines: current status and future prospects.Purification and characterization of retrovirally transduced hematopoietic stem cells.Expression of a swine class II gene in murine bone marrow hematopoietic cells by retroviral-mediated gene transfer.Acid beta-glucosidase: enzymology and molecular biology of Gaucher disease.Gene therapy in thalassemia and hemoglobinopathies.
P2860
Q26859147-F002CB30-FA77-4F0E-B7E0-A1060495300AQ33354120-C00F376D-98B0-4BF6-8C26-4729D5A49969Q33464574-23A53622-6844-4163-AD6D-DE454A0CED02Q33582456-A7403248-E9B7-46F0-BA26-5AEEFEC1C476Q33606876-192B9C30-C2DC-47F1-9221-3D123F169E02Q33619761-ADE1C28E-3897-438C-9CB8-403112375D14Q33926209-161FA84F-99FE-4D4F-84A6-8ED8E8C68E86Q34073641-49A28C11-2ED3-4FDE-90F5-EE8094C134A7Q34220294-C8FFFDDB-220D-41BF-9986-87AEBFA89FA9Q34311947-57E7C833-5E3F-407B-837E-C11773BE12C1Q34319569-A572A0F6-DCD2-4046-A9D0-81850863658DQ34319718-731CB612-6FCA-48D4-A6B1-F75E2E1A00CEQ34326769-8F78C5FD-CB31-488A-8FAE-11ED63DDE693Q34587615-E6FAC8A7-C577-4571-9A93-EF974291B957Q34791132-6BFDCB40-C993-4053-A8FB-519C5002772DQ34958691-5210A3F1-2558-44BB-9677-C9AA18C29464Q34973641-F04628F9-9386-4306-86B3-64BDBCD33F67Q35172449-B6F004BC-E6C3-45FB-9B22-E0EADB428503Q35197045-AFA5600E-768A-4D45-8E2A-EF687C6A2ED3Q35198059-446E41B0-7581-4DB1-BB25-2131349F5B75Q35242925-813DE905-4DFC-434D-B9E9-3A214B52885FQ35604723-7A1C46C3-3402-44A5-A95B-88E04FD818A0Q35837539-89C44303-326A-4B00-BB03-E5CFBB523176Q35898060-ED0572F1-5F0F-47F2-8939-94B7BDC9E3DFQ36230436-D47D9A2C-3CB3-4944-8AB7-6978A0FDB1D1Q36362150-CBEFB73D-CD83-488D-A5CD-99D2528BAD7CQ36872042-FCE826C7-C4A5-452E-B76B-B108D862C305Q36965464-1F1A8E49-E7BA-48B4-8175-A74A7248DAEEQ37142195-C349EBE5-C814-45E8-8545-A3D2B95360A5Q37249173-E02F86C1-D649-46ED-93B1-AB3132944E0CQ37273028-1E40A477-D529-4B8F-AC0B-AFC49AEA188BQ37291677-24112B15-141A-4761-9295-BCC0AB06B24DQ37310938-00F3541B-1801-463B-B37B-10B79026C37CQ37335536-78C49600-78AB-491F-975D-D540D8EB2654Q37384530-9EBD8866-8DA6-42CF-B45E-6EB439F40867Q37422360-82AD2B05-2193-4C15-980E-507F05BE927CQ37599115-6076087F-3ED5-4D52-949E-25D2B5CC205EQ37614002-24AD0876-C16A-4D1F-B21E-F63D38376046Q37832784-E1BC0F86-E10E-4177-B2FD-C45A04A18D95Q37854468-3C053340-AE5C-43C9-9CB2-399E9EF48E89
P2860
Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells
description
1989 nî lūn-bûn
@nan
1989 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Combination of interleukins 3 ...... into hematopoietic stem cells
@ast
Combination of interleukins 3 ...... into hematopoietic stem cells
@en
Combination of interleukins 3 ...... into hematopoietic stem cells
@nl
type
label
Combination of interleukins 3 ...... into hematopoietic stem cells
@ast
Combination of interleukins 3 ...... into hematopoietic stem cells
@en
Combination of interleukins 3 ...... into hematopoietic stem cells
@nl
prefLabel
Combination of interleukins 3 ...... into hematopoietic stem cells
@ast
Combination of interleukins 3 ...... into hematopoietic stem cells
@en
Combination of interleukins 3 ...... into hematopoietic stem cells
@nl
P2093
P2860
P356
P1476
Combination of interleukins 3 ...... into hematopoietic stem cells
@en
P2093
Karlsson S
Nienhuis AW
P2860
P304
P356
10.1073/PNAS.86.22.8897
P407
P577
1989-11-01T00:00:00Z