A comprehensive statistical analysis of predicting in vivo hazard using high-throughput in vitro screening.
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New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformaticsSystems biology and biomarkers of early effects for occupational exposure limit settingThe next generation of risk assessment multiyear study - highlights of findings, applications to risk assessment, and future directionsBig data in chemical toxicity research: the use of high-throughput screening assays to identify potential toxicantsAdvancing human health risk assessment: integrating recent advisory committee recommendationsExposure to Mixtures of Metals and Neurodevelopmental Outcomes: A Multidisciplinary Review Using an Adverse Outcome Pathway FrameworkRecent Advances and Emerging Applications in Text and Data Mining for Biomedical DiscoveryQSAR modeling: where have you been? Where are you going to?Implementation of alternative test strategies for the safety assessment of engineered nanomaterialsQuantitative high-throughput screening data analysis: challenges and recent advancesEstimating Potency in High-Throughput Screening Experiments by Maximizing the Rate of Change in Weighted Shannon EntropyIncorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.Data set modelability by QSARComparison of Points of Departure for Health Risk Assessment Based on High-Throughput Screening Data.Novel Uses of In Vitro Data to Develop Quantitative Biological Activity Relationship Models for in Vivo Carcinogenicity Prediction.A framework for the next generation of risk science.Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing.High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure.FutureTox: building the road for 21st century toxicology and risk assessment practicesIn vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays.Predicting the carcinogenicity of chemicals with alternative approaches: recent advances.The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.Predicting organ toxicity using in vitro bioactivity data and chemical structure.Linking physiological parameters to perturbations in the human exposome: Environmental exposures modify blood pressure and lung function via inflammatory cytokine pathway.Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.Integrated Approaches to Testing and Assessment.Incorporating ToxCast and Tox21 datasets to rank biological activity of chemicals at Superfund sites in North Carolina.Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice.Pathway Based Toxicology and Fit-for-Purpose Assays.In Silico Prediction of Organ Level Toxicity: Linking Chemistry to Adverse Effects.Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays.Alternative Testing Strategies for Nanomaterials: State of the Science and Considerations for Risk Analysis.Integrative chemical-biological read-across approach for chemical hazard classification.Guest editorial: Reassessing animal research ethics.Application of pharmacokinetic modelling for 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure assessment.The Impact of Novel Assessment Methodologies in Toxicology on Green Chemistry and Chemical Alternatives.A framework for an alternatives assessment dashboard for evaluating chemical alternatives applied to flame retardants for electronic applications.Alternative Toxicity Testing: Analyses on Skin Sensitization, ToxCast Phases I and II, and Carcinogenicity Provide Indications on How to Model Mechanisms Linked to Adverse Outcome Pathways.Predictive toxicology today: the transition from biological knowledge to practicable models.
P2860
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P2860
A comprehensive statistical analysis of predicting in vivo hazard using high-throughput in vitro screening.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
A comprehensive statistical an ...... throughput in vitro screening.
@en
A comprehensive statistical an ...... throughput in vitro screening.
@nl
type
label
A comprehensive statistical an ...... throughput in vitro screening.
@en
A comprehensive statistical an ...... throughput in vitro screening.
@nl
prefLabel
A comprehensive statistical an ...... throughput in vitro screening.
@en
A comprehensive statistical an ...... throughput in vitro screening.
@nl
P2093
P50
P356
P1476
A comprehensive statistical an ...... throughput in vitro screening.
@en
P2093
Eric Healy
Russell D Wolfinger
Tzu-Ming Chu
Wenjun Bao
P304
P356
10.1093/TOXSCI/KFS159
P577
2012-04-26T00:00:00Z