Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse.
about
The neurokinin 1 receptor antagonist, ezlopitant, reduces appetitive responding for sucrose and ethanolNeurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neuronsThe pharmacology of neurokinin receptors in addiction: prospects for therapyGut-brain peptides in corticostriatal-limbic circuitry and alcohol use disordersCell-autonomous regulation of Mu-opioid receptor recycling by substance P.Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortexSubpopulations of neurokinin 1 receptor-expressing neurons in the rat lateral amygdala display a differential pattern of innervation from distinct glutamatergic afferentsCell-specific expression of neuropeptide Y Y1 receptor immunoreactivity in the rat basolateral amygdala.Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background.Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues.Increased morphine analgesia and reduced side effects in mice lacking the tac1 gene.Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential.Early Life Stress as a Risk Factor for Substance use Disorders: Clinical and Neurobiological Substrates.Effects of the NK1 antagonist, aprepitant, on response to oral and intranasal oxycodone in prescription opioid abusers.Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429.Reward processing by the opioid system in the brain.Substance P excites GABAergic neurons in the mouse central amygdala through neurokinin 1 receptor activation.Potentiation of brain stimulation reward by morphine: effects of neurokinin-1 receptor antagonism.Stress-related neuropeptides and addictive behaviors: beyond the usual suspects.Opioid-like effects of the neurokinin 1 antagonist aprepitant in patients maintained on and briefly withdrawn from methadone.The NK1 receptor antagonist L822429 reduces heroin reinforcement.Central amygdala GluA1 facilitates associative learning of opioid reward.Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring ratsBuilding a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects.The neurokinin-1 receptor modulates the methamphetamine-induced striatal apoptosis and nitric oxide formation in mice.Emerging targets for addiction neuropharmacology: From mechanisms to therapeuticsNK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD.Neuronal pathways linking substance P to drug addiction and stress.The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seekingArsenic-Induced Activation of the Homeodomain-Interacting Protein Kinase 2 (HIPK2) to cAMP-Response Element Binding Protein (CREB) Axis.Neurokinin 1 and opioid receptors: relationships and interactions in nervous system.[EXPRESS]Analgesia by Deletion of Spinal Neurokinin 1 Receptor Expressing Neurons Using a Bioengineered Substance P-Pseudomonas Exotoxin Conjugate.Sleep and Serotonin Modulate Paracapsular Nitric Oxide Synthase Expressing Neurons of the Amygdala.Anxiety-like behavior is modulated by a discrete subpopulation of interneurons in the basolateral amygdala.The behavioural response of mice lacking NK₁ receptors to guanfacine resembles its clinical profile in treatment of ADHD.Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain.Differential effects of aprepitant, a clinically used neurokinin-1 receptor antagonist on the expression of conditioned psychostimulant versus opioid reward.ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine.Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models.
P2860
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P2860
Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-hans
2003年学术文章
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2003年学术文章
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2003年學術文章
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name
Neurokinin-1 receptor-expressi ...... nxiety behaviors in the mouse.
@en
Neurokinin-1 receptor-expressi ...... nxiety behaviors in the mouse.
@nl
type
label
Neurokinin-1 receptor-expressi ...... nxiety behaviors in the mouse.
@en
Neurokinin-1 receptor-expressi ...... nxiety behaviors in the mouse.
@nl
prefLabel
Neurokinin-1 receptor-expressi ...... nxiety behaviors in the mouse.
@en
Neurokinin-1 receptor-expressi ...... nxiety behaviors in the mouse.
@nl
P2093
P1476
Neurokinin-1 receptor-expressi ...... anxiety behaviors in the mouse
@en
P2093
Carmen De Felipe
Christopher A Gadd
Patricia Murtra
Stephen P Hunt
P304
P356
10.1523/JNEUROSCI.23-23-08271.2003
P407
P577
2003-09-01T00:00:00Z