Retrovirus insertion inactivates mouse alpha 1(I) collagen gene by blocking initiation of transcription.
about
Capture of a cellular transcriptional unit by a retrovirus: mode of provirus activation in embryonal carcinoma cellsTransgenic mouse model of the mild dominant form of osteogenesis imperfectaRestricted expression of Mov13 mutant alpha 1(I) collagen gene in osteoblasts and its consequences for bone developmentA targeted mutation at the known collagenase cleavage site in mouse type I collagen impairs tissue remodelingStructure and expression of a gene encoding a putative GTP-binding protein identified by provirus integration in a transgenic mouse strain.Chromosome structure and human immunodeficiency virus type 1 cDNA integration: centromeric alphoid repeats are a disfavored target.A gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene.Insertional mutation in a transgenic mouse allelic with Purkinje cell degeneration.Characterization of the AdhSL regulatory mutation in Drosophila melanogaster.Interference of the simian virus 40 origin of replication by the cytomegalovirus immediate early gene enhancer: evidence for competition of active regulatory chromatin conformation in a single domain.Targeting the LRP5 pathway improves bone properties in a mouse model of osteogenesis imperfecta.Regulatory elements in the first intron contribute to transcriptional control of the human alpha 1(I) collagen geneRetroviruses as genetic tools to isolate transcriptionally active chromosomal regions.Comparison of promoter suppression in avian and murine retrovirus vectors.Essential role of STAT3 for embryonic stem cell pluripotencyMultiple negative elements in a gene that codes for an extracellular matrix protein, collagen X, restrict expression to hypertrophic chondrocytes.Separate cis-acting DNA elements of the mouse pro-alpha 1(I) collagen promoter direct expression of reporter genes to different type I collagen-producing cells in transgenic miceTissue- and stage-specific activation of an endogenous provirus after transcription through its integration site in the opposite orientationDNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism.An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice.Retrovirus-induced insertional mutagenesis: mechanism of collagen mutation in Mov13 mice.Germ-line transformation of mice.Transcriptionally active genome regions are preferred targets for retrovirus integration.Collagen alpha1(I) gene (COL1A1) is repressed by RFX familyRetrovirus-induced interference with collagen I gene expression in Mov13 fibroblasts is maintained in the absence of DNA methylation.Separable cis-regulatory elements that contribute to tissue- and site-specific alpha 2(XI) collagen gene expression in the embryonic mouse cartilage.Enhanced Wnt signaling improves bone mass and strength, but not brittleness, in the Col1a1(+/mov13) mouse model of type I Osteogenesis Imperfecta.Collagen synthesis by cell lines derived from Mov-13 mouse embryos which have a lethal mutation in the collagen alpha 1(I) gene.
P2860
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P2860
Retrovirus insertion inactivates mouse alpha 1(I) collagen gene by blocking initiation of transcription.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh-hant
name
Retrovirus insertion inactivates mouse alpha 1
@nl
Retrovirus insertion inactivat ...... g initiation of transcription.
@en
type
label
Retrovirus insertion inactivates mouse alpha 1
@nl
Retrovirus insertion inactivat ...... g initiation of transcription.
@en
prefLabel
Retrovirus insertion inactivates mouse alpha 1
@nl
Retrovirus insertion inactivat ...... g initiation of transcription.
@en
P356
P1433
P1476
Retrovirus insertion inactivat ...... g initiation of transcription.
@en
P2093
P2860
P2888
P304
P356
10.1038/320365A0
P407
P577
1986-03-01T00:00:00Z
P6179
1040812160