Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex. - Wikidata - awgldk - TriplyDB

Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex.

Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex.

http://www.wikidata.org/entity/Q44606826

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Proapoptotic BAX and BAK control multiple initiator caspases Ethnopharmacological Significance of Eclipta alba (L.) Hassk. (Asteraceae).Inhibition of Extracellular Calcium Influx Results in Enhanced IL-12 Production in LPS-Treated Murine Macrophages by Downregulation of the CaMKKβ-AMPK-SIRT1 Signaling Pathway Wedelolactone from Eclipta alba inhibits lipopolysaccharide-enhanced cell proliferation of human renal mesangial cells via NF-κB signaling pathway Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-kappaB kinase (IKK) inhibitors.The wedelolactone derivative inhibits estrogen receptor-mediated breast, endometrial, and ovarian cancer cells growth Inflammatory responses in epithelia: endotoxin-induced IL-6 secretion and iNOS/NO production are differentially regulated in mouse mammary epithelial cells.Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.Ethyl acetate extract of Wedelia chinensis inhibits tert-butyl hydroperoxide-induced damage in PC12 cells and D-galactose-induced neuronal cell loss in mice Angiogenin promotes U87MG cell proliferation by activating NF-κB signaling pathway and downregulating its binding partner FHL3 NF-κB addiction and its role in cancer: 'one size does not fit all'.The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat Integrated plasma and urine metabolomics coupled with HPLC/QTOF-MS and chemometric analysis on potential biomarkers in liver injury and hepatoprotective effects of Er-Zhi-Wan.Induction of caspase-11 by aspartyl proteinases of Candida albicans and implication in promoting inflammatory response.Neuroprotective activity of Wedelia calendulacea on cerebral ischemia/reperfusion induced oxidative stress in rats Wedelolactone Regulates Lipid Metabolism and Improves Hepatic Steatosis Partly by AMPK Activation and Up-Regulation of Expression of PPARα/LPL and LDLR Determination of ecliptasaponin A in rat plasma and tissues by liquid chromatography-tandem mass spectrometry.Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis.Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors.Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt.Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic α-cells Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis Wedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation.Minimally modified LDL upregulates endothelin type A receptors in rat coronary arterial smooth muscle cells Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers.Dietary phytochemicals induce p53- and caspase-independent cell death in human neuroblastoma cells.Interleukin-1 stimulates catabolism in C2C12 myotubes.NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals.IκB kinase b Mediating the Downregulation of p53 and p21 by Lipopolysaccharide in Human Papillomavirus 16+ Cervical Cancer Cells.ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer.Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.Apoptosis is induced in Chlamydia trachomatis-infected HEp-2 cells by the addition of a combination innate immune activation compounds and the inhibitor wedelolactone.Inhibitory kappa B Kinases as targets for pharmacological regulation.Modulators of Na/K-ATPase: a patent review.c-Rel Regulates Inscuteable Gene Expression during Mouse Embryonic Stem Cell Differentiation.Wedelolactone, an Anti-inflammatory Botanical, Interrupts c-Myc Oncogenic Signaling and Synergizes with Enzalutamide to Induce Apoptosis in Prostate Cancer Cells.Constituents of the aerial parts of Eclipta prostrata and their cytotoxicity on human ovarian cancer cells in vitro.

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Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex.

http://www.wikidata.org/entity/Q44606826

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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name

Wedelolactone suppresses LPS-i ...... ly inhibiting the IKK complex.

@en

Wedelolactone suppresses LPS-i ...... ly inhibiting the IKK complex.

@nl

type

label

Wedelolactone suppresses LPS-i ...... ly inhibiting the IKK complex.

@en

Wedelolactone suppresses LPS-i ...... ly inhibiting the IKK complex.

@nl

prefLabel

Wedelolactone suppresses LPS-i ...... ly inhibiting the IKK complex.

@en

Wedelolactone suppresses LPS-i ...... ly inhibiting the IKK complex.

@nl

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Cell Death & Differentiation

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Wedelolactone suppresses LPS-i ...... ly inhibiting the IKK complex.

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A Rao

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C Yuan

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D Gong

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F Ikegami

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H Zhu

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J Yuan

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M Angelica M Gakidis

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M Kobori

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T Sekine

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V Heissmeyer

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P2860

Analysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activity

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions.

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase.

Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma.

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10.1038/SJ.CDD.4401325

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1

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