Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.
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NF-κB and stat3 transcription factor signatures differentiate HPV-positive and HPV-negative head and neck squamous cell carcinoma.MEK inhibitor PD-0325901 overcomes resistance to CK2 inhibitor CX-4945 and exhibits anti-tumor activity in head and neck cancer.Comprehensive Evaluation of Nuclear Factor-κΒ Expression Patterns in Non-Small Cell Lung Cancer.Gastro-duodenal fluid induced nuclear factor-κappaB activation and early pre-malignant alterations in murine hypopharyngeal mucosaA positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-kB regulates head and neck squamous cell carcinoma proliferation.TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.IκB kinase b Mediating the Downregulation of p53 and p21 by Lipopolysaccharide in Human Papillomavirus 16+ Cervical Cancer Cells.The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes.Characterization of key transcription factors as molecular signatures of HPV-positive and HPV-negative oral cancers.ErbB Family Signalling: A Paradigm for Oncogene Addiction and Personalized Oncology.In vitro model for gastroduodenal reflux-induced nuclear factor-kappaB activation and its role in hypopharyngeal carcinogenesis.Emerging Roles for Noncanonical NF-κB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology.Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing miR-29b and regulating cell apoptosis.IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development.Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding.A link between RelB expression and tumor progression in laryngeal cancer.Bioluminescence Imaging to Monitor the Effects of the Hsp90 Inhibitor NVP-AUY922 on NF-κB Pathway in Endometrial Cancer.Inhibition of NF-κB prevents the acidic bile-induced oncogenic mRNA phenotype, in human hypopharyngeal cells.Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.Targeting IκappaB kinases for cancer therapy.NF-κB inhibition reverses acidic bile-induced miR-21, miR-155, miR-192, miR-34a, miR-375 and miR-451a deregulations in human hypopharyngeal cells.In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile-Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa.BRCA1 Mutation Status and Follicular Fluid Exposure Alters NFκB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells.Curcumin prevents the bile reflux-induced NF-κB-related mRNA oncogenic phenotype, in human hypopharyngeal cellsTargeting IKKβ in Cancer: Challenges and Opportunities for the Therapeutic Utilisation of IKKβ Inhibitors
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Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Aberrant IKKα and IKKβ coopera ...... ation of head and neck cancer.
@en
Aberrant IKKα and IKKβ coopera ...... ation of head and neck cancer.
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type
label
Aberrant IKKα and IKKβ coopera ...... ation of head and neck cancer.
@en
Aberrant IKKα and IKKβ coopera ...... ation of head and neck cancer.
@nl
prefLabel
Aberrant IKKα and IKKβ coopera ...... ation of head and neck cancer.
@en
Aberrant IKKα and IKKβ coopera ...... ation of head and neck cancer.
@nl
P2093
P2860
P356
P1433
P1476
Aberrant IKKα and IKKβ coopera ...... ation of head and neck cancer.
@en
P2093
C Van Waes
L K Nottingham
P2860
P2888
P304
P356
10.1038/ONC.2013.49
P407
P577
2013-03-04T00:00:00Z