Reversal of tumorigenicity and the block to differentiation in erythroleukemia cells by GATA-1.
about
P1343
GATA-1 associates with and inhibits p53.Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and developmentPU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cellsRepression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturationA large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure.GATA-1 directly regulates p21 gene expression during erythroid differentiationStat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiationReprogramming leukemia cells to terminal differentiation and growth arrest by RNA interference of PU.1.MAPK-mediated phosphorylation of GATA-1 promotes Bcl-XL expression and cell survival.GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in ErythroleukemiaSpi-1 and Fli-1 directly activate common target genes involved in ribosome biogenesis in Friend erythroleukemic cells.Multi-stage Friend murine erythroleukemia: molecular insights into oncogenic cooperation.PU.1 activation relieves GATA-1-mediated repression of Cebpa and Cbfb during leukemia differentiation.CDC6 expression is regulated by lineage-specific transcription factor GATA1.A novel transcript of the LMO2 gene, LMO2-c, is regulated by GATA-1 and PU.1 and encodes an antagonist of LMO2.
P2860
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P2860
Reversal of tumorigenicity and the block to differentiation in erythroleukemia cells by GATA-1.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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name
Reversal of tumorigenicity and ...... ythroleukemia cells by GATA-1.
@en
Reversal of tumorigenicity and ...... ythroleukemia cells by GATA-1.
@nl
type
label
Reversal of tumorigenicity and ...... ythroleukemia cells by GATA-1.
@en
Reversal of tumorigenicity and ...... ythroleukemia cells by GATA-1.
@nl
prefLabel
Reversal of tumorigenicity and ...... ythroleukemia cells by GATA-1.
@en
Reversal of tumorigenicity and ...... ythroleukemia cells by GATA-1.
@nl
P2093
P1433
P1476
Reversal of tumorigenicity and ...... ythroleukemia cells by GATA-1.
@en
P2093
Arthur I Skoultchi
Farshid Radparvar
Igor Matushansky
Kevin S Choe
Natasha Rekhtman
P304
P407
P4510
P577
2003-10-01T00:00:00Z