Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells.
about
The 100-kDa 2',5'-oligoadenylate synthetase catalyzing preferentially the synthesis of dimeric pppA2'p5'A molecules is composed of three homologous domainsThe nature of the catalytic domain of 2'-5'-oligoadenylate synthetasesCharacterization of the 2'-5'-oligoadenylate synthetase ubiquitin-like familyA dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferonNew insights into the role of RNase L in innate immunityDiverse functions of RNase L and implications in pathologyA scientific journey through the 2-5A/RNase L systemViral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral responseThe Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate ResponsePositional cloning of the murine flavivirus resistance geneCharacterization of the equine 2'-5' oligoadenylate synthetase 1 (OAS1) and ribonuclease L (RNASEL) innate immunity genesStructure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate ImmunityTo translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genesGermline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast cancer.2',5'-oligoadenylate synthetase induction in lymphocytes of patients with connective tissue diseasesOAS1 polymorphisms are associated with susceptibility to West Nile encephalitis in horsesThe search for guanosine tetraphosphate (ppGpp) and other unusual nucleotides in eucaryotesRNase L mediates the antiviral effect of interferon through a selective reduction in viral RNA during encephalomyocarditis virus infectionInterferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase LInduction of 2',5'-oligoadenylate synthetase and interferon in mouse trigeminal ganglia infected with herpes simplex virus.Interferon-induced proteins in human fibroblasts and development of the antiviral state.Regulation of protein synthesis: activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2.RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP.Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cellsOASes and STING: adaptive evolution in concertChemical synthesis and biological activities of analogues of 2',5'-oligoadenylates containing 8-substituted adenosine derivatives.Responses of insect cells to baculovirus infection: protein synthesis shutdown and apoptosis.Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery.5'-O-Monophosphoryladenylyl(2' goes to 5')adenylyl(2' goes to 5')adenosine is an antagonist of the action of 5'-O-triphosphoryladenylyl-(2' goes to 5')adenylyl(2' goes to 5')adenosine and double-stranded RNA.Species specificity of interferon action: maintenance and establishment of the antiviral state in the presence of a heterospecific nucleus.Injection of mice with antibody to mouse interferon alpha/beta decreases the level of 2'-5' oligoadenylate synthetase in peritoneal macrophages.Synthesis of (2'-5')oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirusA mammalian 2-5A system functions as an antiviral pathway in transgenic plants.Double-stranded RNA-dependent phosphorylation of protein P1 and eukaryotic initiation factor 2 alpha does not correlate with protein synthesis inhibition in a cell-free system from interferon-treated mouse L cells.2'-5' Oligoadenylate synthetase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells.Catalytic cleavage of an RNA target by 2-5A antisense and RNase L.Structural basis for recognition of 2',5'-linked oligoadenylates by human ribonuclease L.Activation of RNase L by 2',5'-oligoadenylates. Kinetic characterization.Activation of RNase L by 2',5'-oligoadenylates. Biophysical characterization.Killing of cancer cells through the use of eukaryotic expression vectors harbouring genes encoding nucleases and ribonuclease inhibitor.
P2860
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P2860
Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年学术文章
@wuu
1977年学术文章
@zh
1977年学术文章
@zh-cn
1977年学术文章
@zh-hans
1977年学术文章
@zh-my
1977年学术文章
@zh-sg
1977年學術文章
@yue
1977年學術文章
@zh-hant
name
Synthesis of low molecular wei ...... from interferon-treated cells.
@en
Synthesis of low molecular wei ...... from interferon-treated cells.
@nl
type
label
Synthesis of low molecular wei ...... from interferon-treated cells.
@en
Synthesis of low molecular wei ...... from interferon-treated cells.
@nl
prefLabel
Synthesis of low molecular wei ...... from interferon-treated cells.
@en
Synthesis of low molecular wei ...... from interferon-treated cells.
@nl
P2093
P2860
P356
P1433
P1476
Synthesis of low molecular wei ...... from interferon-treated cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/268537A0
P407
P577
1977-08-01T00:00:00Z
P6179
1014596186