Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice.
about
Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6Interleukin-6 deficiency increases inflammatory bone destructionThe anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strainSTAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia.Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling.IL-1-induced murine osteoblast IL-6 production is mediated by the type 1 IL-1 receptor and is increased by 1,25 dihydroxyvitamin D3.Reduction of particle-induced osteolysis by interleukin-6 involves anti-inflammatory effect and inhibition of early osteoclast precursor differentiationInduction of cachexia in mice by a product isolated from the urine of cachectic cancer patients.Pathophysiology of cancer cachexia.Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivoRegulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptorConsistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouseInterleukin-6/soluble interleukin-6 receptor signaling attenuates proliferation and invasion, and induces morphological changes of a newly established pleomorphic malignant fibrous histiocytoma cell line.Divergency of leptin response in intestinal inflammation17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens.Evidence for the involvement of interleukin 6 in experimental cancer cachexia.Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient miceBone marrow neutrophilia and suppressed bone turnover in human interleukin-6 transgenic mice. A cellular relationship among hematopoietic cells, osteoblasts, and osteoclasts mediated by stromal cells in bone marrowInterleukin-6 cDNA transfected Lewis lung carcinoma cells show unaltered net tumour growth rate but cause weight loss and shortened survival in syngeneic mice.Inflammation, organomegaly, and muscle wasting despite hyperphagia in a mouse model of burn cachexia.Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitorsMultiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia.STAT3 in the systemic inflammation of cancer cachexia.Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency.Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting.Expression levels of gp130 in bone marrow stromal cells determine the magnitude of osteoclastogenic signals generated by IL-6-type cytokines.Autocrine regulation of osteoclast formation and bone resorption by IL-1 alpha and TNF alpha.Combination of telmisartan with cisplatin controls oral cancer cachexia in rats.Functional heterogeneity and pathogenic significance of interleukin-6 in B-cell lymphomas.Effect of estrogen deficiency on skeletal and alveolar bone density in sheep.Stimulation of cells derived from nifedipine-induced gingival overgrowth with Porphyromonas gingivalis, lipopolysaccharide, and interleukin-1beta.Metabolic Changes During Cancer Cachexia Pathogenesis.Characterization of mice bearing subclones of colon 26 adenocarcinoma disqualifies interleukin-6 as the sole inducer of cachexia.
P2860
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P2860
Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
Chinese hamster ovarian cells ...... is in tumor-bearing nude mice.
@en
Chinese hamster ovarian cells ...... is in tumor-bearing nude mice.
@nl
type
label
Chinese hamster ovarian cells ...... is in tumor-bearing nude mice.
@en
Chinese hamster ovarian cells ...... is in tumor-bearing nude mice.
@nl
prefLabel
Chinese hamster ovarian cells ...... is in tumor-bearing nude mice.
@en
Chinese hamster ovarian cells ...... is in tumor-bearing nude mice.
@nl
P2093
P356
P1433
P1476
Chinese hamster ovarian cells ...... is in tumor-bearing nude mice.
@en
P2093
P304
P356
10.1210/ENDO-128-5-2657
P407
P577
1991-05-01T00:00:00Z