Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. - Wikidata - awgldk - TriplyDB

Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium.

Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium.

http://www.wikidata.org/entity/Q44715726

about

A developmental sex difference in hippocampal neurogenesis is mediated by endogenous oestradiol Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia Glutamate and neurotrophic factors in neuronal plasticity and disease Epigenetic mechanisms in schizophrenia Abnormalities in the fatty acid composition of the postmortem orbitofrontal cortex of schizophrenic patients: gender differences and partial normalization with antipsychotic medications Reelin Proteolysis Affects Signaling Related to Normal Synapse Function and Neurodegeneration Neuronal networks in mental diseases and neuropathic pain: Beyond brain derived neurotrophic factor and collapsin response mediator proteins Comorbidity Factors and Brain Mechanisms Linking Chronic Stress and Systemic Illness Reelin-Related Disturbances in Depression: Implications for Translational Studies GABA abnormalities in schizophrenia: a methodological review of in vivo studies Tiagabine improves hippocampal long-term depression in rat pups subjected to prenatal inflammation BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes Proteomic analysis of rat hippocampus exposed to the antidepressant paroxetine Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications.Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia.Functional interactions between steroid hormones and neurotrophin BDNF A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility Reelin Regulates the Maturation of Dendritic Spines, Synaptogenesis and Glial Ensheathment of Newborn Granule Cells.Development of antipsychotic medications with novel mechanisms of action based on computational modeling of hippocampal neuropathology.The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment Genetic control of individual differences in gene-specific methylation in human brain.Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder.N-methyl-D-aspartate receptor expression in parvalbumin-containing inhibitory neurons in the prefrontal cortex in bipolar disorder Association study of SNAP25 and schizophrenia in Irish family and case-control samples.The selective glucocorticoid receptor antagonist CORT 108297 decreases neuroendocrine stress responses and immobility in the forced swim test.Chronic lithium treatment elicits its antimanic effects via BDNF-TrkB dependent synaptic downscaling Brain gamma-aminobutyric acid (GABA) abnormalities in bipolar disorder Hippocampal subfield volumes in mood disorders Oxidative damage to RNA but not DNA in the hippocampus of patients with major mental illness.Neurotrophin receptors expression in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with seizure type and surgical outcome.Tensor-based morphometry and stereology reveal brain pathology in the complexin1 knockout mouse The methylazoxymethanol acetate (MAM-E17) rat model: molecular and functional effects in the hippocampus.Loss of pattern separation performance in schizophrenia suggests dentate gyrus dysfunction Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases.Bipolar disorder type 1 and schizophrenia are accompanied by decreased density of parvalbumin- and somatostatin-positive interneurons in the parahippocampal region.Novel animal models for studying complex brain disorders: BAC-driven miRNA-mediated in vivo silencing of gene expression.

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Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium.

http://www.wikidata.org/entity/Q44715726

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Molecular Psychiatry

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Molecular abnormalities of the ...... ley Neuropathology Consortium.

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Beata M Barci

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E Fuller Torrey

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James Meador-Woodruff

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Maree J Webster

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Michael B Knable

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Stanley Neuropathology Consortium

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P2860

A decrease of reelin expression as a putative vulnerability factor in schizophrenia

Markers close to the dopamine D5 receptor gene (DRD5) show significant association with schizophrenia but not bipolar disorder

The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

Cell biology of the hippocampal formation in schizophrenia.

Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression.

Studies in animal models and humans suggesting a role of nerve growth factor in schizophrenia-like disorders.

Altered levels of Reelin and its isoforms in schizophrenia and mood disorders.

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10.1038/SJ.MP.4001471

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