5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.
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5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Abeta peptide-induced inflammatory mediators in astroglia.Redox regulation of mitochondrial biogenesisControls of Nuclear Factor-Kappa B Signaling Activity by 5'-AMP-Activated Protein Kinase Activation With Examples in Human Bladder Cancer CellsPKC-dependent human monocyte adhesion requires AMPK and Syk activationAICAR Enhances the Phagocytic Ability of Macrophages towards Apoptotic Cells through P38 Mitogen Activated Protein Kinase Activation Independent of AMP-Activated Protein KinaseFunctional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cellsA network pharmacology approach to establish the pharmacological mechanism of JiaWeiXianJiTang on inflammatory bowel diseaseRoscovitine protects murine Leydig cells from lipopolysaccharide-induced inflammationNutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.Adaptive brain shut-down counteracts neuroinflammation in the near-term ovine fetusLipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment.AMPK-NF-κB axis in the photoreceptor disorder during retinal inflammationMolecular insights and therapeutic targets for diabetic endothelial dysfunction.Putative Role of AMPK in Fetal Adaptive Brain Shut-Down: Linking Metabolism and Inflammation in the Brain.AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes.Metformin Improves Insulin Signaling in Obese Rats via Reduced IKKbeta Action in a Fiber-Type Specific Manner.Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosisThe microtubule-associated protein EB1 links AIM2 inflammasomes with autophagy-dependent secretion.Isoform-selective 5'-AMP-activated protein kinase-dependent preconditioning mechanisms to prevent postischemic leukocyte-endothelial cell adhesive interactions.Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system.AMP-activated protein kinase suppresses matrix metalloproteinase-9 expression in mouse embryonic fibroblasts.AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice modelImmunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitisResveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells.Elevated NF-κB activation is conserved in human myocytes cultured from obese type 2 diabetic patients and attenuated by AMP-activated protein kinaseAICAR attenuates organ injury and inflammatory response after intestinal ischemia and reperfusion.Post-treatment with the combination of 5-aminoimidazole-4-carboxyamide ribonucleoside and carnitine improves renal function after ischemia/reperfusion injuryAdenosine Monophosphate-activated Protein Kinase Regulates Interleukin-1β Expression and Glial Glutamate Transporter Function in Rodents with Neuropathic Pain.AMPK-Activated Protein Kinase Suppresses Ccr2 Expression by Inhibiting the NF-κB Pathway in RAW264.7 MacrophagesFlavonoids of Polygonum hydropiper L. attenuates lipopolysaccharide-induced inflammatory injury via suppressing phosphorylation in MAPKs pathways.Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a high-fat diet.Triggering receptor expressed on myeloid cells and 5'adenosine monophosphate-activated protein kinase in the inflammatory response: a potential therapeutic target.Aminoimidazole carboxamide ribonucleotide ameliorates experimental autoimmune uveitisDefining the molecular nexus of cancer, type 2 diabetes and cardiovascular disease.Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells.Stimulation of Brain AMP-Activated Protein Kinase Attenuates Inflammation and Acute Lung Injury in SepsisTwo discreet subsets of CD8 T cells modulate PLP(91-110) induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice.Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence.Genetic deletion of catalytic subunits of AMP-activated protein kinase increases osteoclasts and reduces bone mass in young adult mice.
P2860
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P2860
5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
5-aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@en
5-aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@nl
type
label
5-aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@en
5-aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@nl
prefLabel
5-aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@en
5-aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@nl
P2093
P1476
5-aminoimidazole-4-carboxamide ...... f AMP-activated protein kinase
@en
P2093
Avtar K Singh
Brian Smith
Inderjit Singh
Narendra Nath
Shailendra Giri
P304
P356
10.1523/JNEUROSCI.4288-03.2004
P407
P577
2004-01-01T00:00:00Z