Serotonin stimulates DNA synthesis in fibroblasts acting through 5-HT1B receptors coupled to a Gi-protein.
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Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenesActivation of 5-HT1A receptors expressed in NIH-3T3 cells induces focus formation and potentiates EGF effect on DNA synthesisG-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicityActivation of the beta 2-adrenergic receptor promotes growth and differentiation in thyroid cellsNeural and cardiac toxicities associated with 3,4-methylenedioxymethamphetamine (MDMA)Dual dopamine/serotonin releasers: potential treatment agents for stimulant addictionSerotonergic drugs and valvular heart diseaseEchocardiographic evidence for valvular toxicity of benfluorex: a double-blind randomised trial in patients with type 2 diabetes mellitusDiversity of G proteins in signal transductionAndrogen-repressed phenotype in human prostate cancer.Expression of serotonin receptor 2c in rat type II pneumocytes.The recombinant 5-HT1A receptor: G protein coupling and signalling pathways.Development of inhibitors of heterotrimeric Gαi subunitsImpact of serotonin on tumour growth.A murine model of the eosinophilia-myalgia syndrome induced by 1,1'-ethylidenebis (L-tryptophan).The expression and function of G-proteins in experimental intimal hyperplasiaMast cell tryptase is a mitogen for cultured fibroblasts.L-tryptophan implicated in human eosinophilia-myalgia syndrome causes fasciitis and perimyositis in the Lewis rat.Distribution of serotonin 5-HT1C receptor mRNA in adult rat brain.Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCbeta-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle.5-hydroxytryptamine 2B receptor regulates cell-cycle progression: cross-talk with tyrosine kinase pathwaysDopamine receptors and Parkinson's diseaseShort-term regulation of Na+/K+ adenosine triphosphatase by recombinant human serotonin 5-HT1A receptor expressed in HeLa cellsInvolvement of transforming growth factor-beta in the formation of fibrotic lesions in carcinoid heart disease.The 5-hydroxytryptamine transporter is functional in human coronary artery smooth muscle cells proliferation and is regulated by Interleukin-1 beta.Serotonin expression in pancreatic neuroendocrine tumors correlates with a trabecular histologic pattern and large duct involvementStimulation of human thyroid growth via the inhibitory guanine nucleotide binding (G) protein Gi: constitutive expression of the G-protein alpha subunit Gi alpha-1 in autonomous adenoma.Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation.The effect of 5-hydroxtryptamine on the regulation of megakaryocytopoiesis.Role of the serotonergic system in alcohol dependence: from animal models to clinics.Mitogenic effects of fibroblast growth factors in cultured fibroblasts. Interaction with the G-protein-mediated signaling pathways.Role of 5-hydroxytryptamine 1B (5-HT1B) receptors in the regulation of ethanol intake in rodents.Evidence for the implication of phosphoinositol signal transduction in mu-opioid inhibition of DNA synthesisSerotonin: good or bad for bone.Appetite suppressants, cardiac valve disease and combination pharmacotherapy5-HT receptors: subtypes and second messengers.Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells.A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells.Activating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells.
P2860
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P2860
Serotonin stimulates DNA synthesis in fibroblasts acting through 5-HT1B receptors coupled to a Gi-protein.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Serotonin stimulates DNA synth ...... ptors coupled to a Gi-protein.
@en
Serotonin stimulates DNA synth ...... ptors coupled to a Gi-protein.
@nl
type
label
Serotonin stimulates DNA synth ...... ptors coupled to a Gi-protein.
@en
Serotonin stimulates DNA synth ...... ptors coupled to a Gi-protein.
@nl
prefLabel
Serotonin stimulates DNA synth ...... ptors coupled to a Gi-protein.
@en
Serotonin stimulates DNA synth ...... ptors coupled to a Gi-protein.
@nl
P2093
P356
P1433
P1476
Serotonin stimulates DNA synth ...... ptors coupled to a Gi-protein.
@en
P2093
Magnaldo I
Pouysségur J
P2888
P304
P356
10.1038/335254A0
P407
P577
1988-09-01T00:00:00Z
P6179
1009381863