Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats.

Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats.

Item
http://www.wikidata.org/entity/Q44731939
A Liver-Centric Multiscale Modeling Framework for XenobioticsInvestigation of ifosfamide and chloroacetaldehyde renal toxicity through integration of in vitro liver-kidney microfluidic data and pharmacokinetic-system biology models.Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling.Inability to maintain GSH pool in G6PD-deficient red cells causes futile AMPK activation and irreversible metabolic disturbanceHuman biology-based drug safety evaluation: scientific rationale, current status and future challenges.Investigation of acetaminophen toxicity in HepG2/C3a microscale cultures using a system biology model of glutathione depletion.A novel approach for estimating ingested dose associated with paracetamol overdose.Modeling Pharmacokinetics.Characterizing the Effects of Race/Ethnicity on Acetaminophen Pharmacokinetics Using Physiologically Based Pharmacokinetic Modeling.Metabolic changes in the urine of andrographolide sodium bisulfite-treated rats.Physiologically based modeling of the pharmacokinetics of acetaminophen and its major metabolites in humans using a Bayesian population approach.Computational Modeling in Liver Surgery.First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans.An introduction to systems toxicology
P2860

Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats.

Item
http://www.wikidata.org/entity/Q44731939
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Multiscale modelling approach ...... oxoproline in humans and rats.
@en
Multiscale modelling approach ...... oxoproline in humans and rats.
@nl
type
label
Multiscale modelling approach ...... oxoproline in humans and rats.
@en
Multiscale modelling approach ...... oxoproline in humans and rats.
@nl
prefLabel
Multiscale modelling approach ...... oxoproline in humans and rats.
@en
Multiscale modelling approach ...... oxoproline in humans and rats.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Multiscale modelling approach ...... oxoproline in humans and rats.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921