Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
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Alzheimer mechanisms and therapeutic strategiesImmunization with amyloid-beta attenuates inclusion body myositis-like myopathology and motor impairment in a transgenic mouse modelProtein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseasesActive and passive immunotherapy for neurodegenerative disordersTau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's DiseasePrion diseases: immunotargets and therapyNeuroprotective and Therapeutic Strategies against Parkinson's Disease: Recent PerspectivesMechanism of Anti-α-Synuclein ImmunotherapyImmunotherapy in Parkinson's Disease: Micromanaging Alpha-Synuclein AggregationDisease-modifying therapeutic directions for Lewy-Body dementiasInsights into Neuroinflammation in Parkinson's Disease: From Biomarkers to Anti-Inflammatory Based TherapiesThe complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's diseaseProteolytic clearance of extracellular α-synuclein as a new therapeutic approach against Parkinson diseaseVaccination strategies for Parkinson disease: induction of a swift attack or raising tolerance?Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic targetTau-targeted treatment strategies in Alzheimer's diseaseNeuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunityAlpha-Synuclein Oligomers-Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body DisordersFriend or foe: the dichotomous impact of T cells on neuro-de/re-generation during agingImmunotherapeutic approaches for Alzheimer's diseaseThe HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathyPassive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body diseaseAntibodies against alpha-synuclein reduce oligomerization in living cellsRepression of alpha-synuclein expression and toxicity by microRNA-7.Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease.Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials.ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicityAssessment of rat and mouse RGC apoptosis imaging in vivo with different scanning laser ophthalmoscopesDirected selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils.Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze?Detecting morphologically distinct oligomeric forms of alpha-synuclein.Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinson's disease.Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseasesRationale for therapeutic silencing of alpha-synuclein in Parkinson's diseaseSelective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathyStructure, Distribution, and Genetic Profile of α-Synuclein and Their Potential Clinical Application in Parkinson's Disease.The Cleavage Effect of Mesenchymal Stem Cell and Its Derived Matrix Metalloproteinase-2 on Extracellular α-Synuclein Aggregates in Parkinsonian ModelsDirect transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies.
P2860
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P2860
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
@en
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
@nl
type
label
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
@en
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
@nl
prefLabel
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
@en
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
@nl
P2093
P50
P921
P1433
P1476
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
@en
P2093
Anthony Adame
Dale Schenk
Dora Games
Jason Goldstein
Makoto Hashimoto
Michael Alford
Michael Lee
Peter Seubert
Tamie Chilcote
P304
P356
10.1016/J.NEURON.2005.05.010
P407
P577
2005-06-01T00:00:00Z