Analysis of mutations in the Tk gene of Tk(+/-) mice treated as neonates with 3'-azido-3'-deoxythymidine (AZT).
about
Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cellsInhibition of NF-κB activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis3'-azido-3'-deoxythymidine induces deletions in L5178Y mouse lymphoma cells.Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations.Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.Micronuclei induced by reverse transcriptase inhibitors in mononucleated and binucleated cells as assessed by the cytokinesis-block micronucleus assay.Comparative analysis of genetic toxicity of AZT and ddI antiretrovirals in somatic cells of Drosophila melanogaster.Transplacental drug transfer and frequency of Tk and Hprt lymphocyte mutants and peripheral blood micronuclei in mice treated transplacentally with zidovudine and lamivudine.Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53-haplodeficient mice treated perinatally with AZT and AZT in combination with 3TC.
P2860
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P2860
Analysis of mutations in the Tk gene of Tk(+/-) mice treated as neonates with 3'-azido-3'-deoxythymidine (AZT).
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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name
Analysis of mutations in the Tk gene of Tk
@nl
Analysis of mutations in the T ...... azido-3'-deoxythymidine (AZT).
@en
type
label
Analysis of mutations in the Tk gene of Tk
@nl
Analysis of mutations in the T ...... azido-3'-deoxythymidine (AZT).
@en
prefLabel
Analysis of mutations in the Tk gene of Tk
@nl
Analysis of mutations in the T ...... azido-3'-deoxythymidine (AZT).
@en
P2093
P1433
P1476
Analysis of mutations in the T ...... azido-3'-deoxythymidine (AZT).
@en
P2093
Joseph G Shaddock
Linda S Von Tungeln
Robert H Heflich
Roberta A Mittelstaedt
Vasily N Dobrovolsky
P356
10.1016/J.MRFMMM.2003.12.008
P407
P577
2004-03-01T00:00:00Z