Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
about
N-{N-[2-(3,5-Difluorophenyl)acetyl]-(S)-alanyl}-(S)-phenylglycine tert-butyl ester (DAPT): an inhibitor of γ-secretase, revealing fine electronic and hydrogen-bonding features.Presenilin-dependent intramembrane cleavage of ephrin-B1.Binding of longer Aβ to transmembrane domain 1 of presenilin 1 impacts on Aβ42 generationSynthesis and biological activity of N-substituted spiro[benzoxazepine-piperidine] Aβ-peptide production inhibitors
P2860
Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
description
2004 nî lūn-bûn
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2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
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2004年學術文章
@zh-hant
name
Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
@en
Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
@nl
type
label
Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
@en
Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
@nl
prefLabel
Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
@en
Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
@nl
P2093
P1476
Parallel synthesis of DAPT derivatives and their gamma-secretase-inhibitory activity.
@en
P2093
Hideaki Natsugari
Kentaro Rikimaru
Takeshi Iwatsubo
Tohru Fukuyama
Toshiyuki Kan
Yuichi Morohashi
Yusuke Tominari
P304
P356
10.1016/J.BMCL.2004.01.067
P407
P577
2004-04-01T00:00:00Z