Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent.
about
IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasisCellular and molecular mechanisms of fibrosisMacrophage and Innate Lymphoid Cell Interplay in the Genesis of FibrosisSchistosomiasis-associated pulmonary hypertensionRole of IL-4Rα during acute schistosomiasis in miceCD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infectionPurinergic P2Y12 Receptor Activation in Eosinophils and the Schistosomal Host ResponseElevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infectionPurinergic signaling in schistosomal infectionPulmonary fibrosis: pathogenesis, etiology and regulationAlterations of serum biomarkers associated with lung ventilation function impairment in coal workers: a cross-sectional studyDirect regulation of Gata3 expression determines the T helper differentiation potential of NotchImmune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heartRegulation of innate responses during pre-patent schistosome infection provides an immune environment permissive for parasite development.Differential liver protein expression during schistosomiasis.Cationic amino acid transporter-2 regulates immunity by modulating arginase activity.Detecting the effects of selection at the population level in six bovine immune genesAccelerated and progressive and lethal liver fibrosis in mice that lack interleukin (IL)-10, IL-12p40, and IL-13Rα2.Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosisRetnla (relmalpha/fizz1) suppresses helminth-induced Th2-type immunity.IL-4Ralpha-independent expression of mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness.Silymarin reduces profibrogenic cytokines and reverses hepatic fibrosis in chronic murine schistosomiasis.Induction of type 2 responses by schistosome worms during prepatent infection.Single-sex infection with female Schistosoma mansoni cercariae mitigates hepatic fibrosis after secondary infectionTh1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection.Severe schistosomiasis in the absence of interleukin-4 (IL-4) is IL-12 independentInterleukin-12 promotes pathologic liver changes and death in mice coinfected with Schistosoma mansoni and Toxoplasma gondiiRole of gamma interferon in the pathogenesis of severe schistosomiasis in interleukin-4-deficient mice.Hepatic stellate cells and parasite-induced liver fibrosis.Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasisIL-4R alpha expression by bone marrow-derived cells is necessary and sufficient for host protection against acute schistosomiasis.Ly6Chi monocyte recruitment is responsible for Th2 associated host-protective macrophage accumulation in liver inflammation due to schistosomiasis.Central role for interleukin-4 in regulating nitric oxide-mediated inhibition of T-cell proliferation and gamma interferon production in schistosomiasisImmunology of parasitic helminth infections.Dexamethasone, a drug for attenuation of Schistosoma mansoni infection morbidityIL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease.Interleukins in chronic liver disease: lessons learned from experimental mouse modelsType 1 T helper cells induce the accumulation of myeloid-derived suppressor cells in the inflamed Tgfb1 knockout mouse liver.Incomplete deletion of IL-4Rα by LysM(Cre) reveals distinct subsets of M2 macrophages controlling inflammation and fibrosis in chronic schistosomiasis.Lipocalin allergens.
P2860
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P2860
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Schistosome infection of trans ...... IL-13 is a profibrotic agent.
@en
Schistosome infection of trans ...... IL-13 is a profibrotic agent.
@nl
type
label
Schistosome infection of trans ...... IL-13 is a profibrotic agent.
@en
Schistosome infection of trans ...... IL-13 is a profibrotic agent.
@nl
prefLabel
Schistosome infection of trans ...... IL-13 is a profibrotic agent.
@en
Schistosome infection of trans ...... IL-13 is a profibrotic agent.
@nl
P2093
P1476
Schistosome infection of trans ...... IL-13 is a profibrotic agent.
@en
P2093
McKenzie AN
McKenzie GJ
Richardson EJ
P304
P356
10.4049/JIMMUNOL.164.5.2585
P407
P577
2000-03-01T00:00:00Z