Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1.
about
Using engineered 2-O-sulfotransferase to determine the activity of heparan sulfate C5-epimerase and its mutantsCatalytic mechanism of Golgi-resident human tyrosylprotein sulfotransferase-2: a mass spectrometry approachUnderstanding the substrate specificity of the heparan sulfate sulfotransferases by an integrated biosynthetic and crystallographic approachRedirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesisDissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparinStructural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesisA Simple Method for Discovering Druggable, Specific Glycosaminoglycan-Protein Systems. Elucidation of Key Principles from Heparin/Heparan Sulfate-Binding ProteinsToward an artificial Golgi: redesigning the biological activities of heparan sulfate on a digital microfluidic chip.Enzymatic synthesis of heparin related polysaccharides on sensor chips: rapid screening of heparin-protein interactions.Using an enzymatic combinatorial approach to identify anticoagulant heparan sulfate structures.Chemoenzymatic design of heparan sulfate oligosaccharidesHeparan sulfate 3-O-sulfation: a rare modification in search of a function.CS lyases: structure, activity, and applications in analysis and the treatment of diseasesEnzymatic redesigning of biologically active heparan sulfate.Mutational study of heparan sulfate 2-O-sulfotransferase and chondroitin sulfate 2-O-sulfotransferase.Structural characterization of heparins from different commercial sourcesDirecting the biological activities of heparan sulfate oligosaccharides using a chemoenzymatic approachAnticoagulant heparan sulfate: structural specificity and biosynthesis.Recent advances in sulfotransferase enzyme activity assays.Distinct 3-O-sulfated heparan sulfate modification patterns are required for kal-1-dependent neurite branching in a context-dependent manner in Caenorhabditis elegans.Enzymatic synthesis of glycosaminoglycan heparinIsotope exchange at equilibrium indicates a steady state ordered kinetic mechanism for human sulfotransferase.An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence.Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases.Structural Analysis of Heparin-Derived 3-O-Sulfated Tetrasaccharides: Antithrombin Binding Site Variants.Insights into the reaction mechanism of 3-O-sulfotransferase through QM/MM calculations.Assays for determining heparan sulfate and heparin O-sulfotransferase activity and specificity.Affinity, kinetic, and structural study of the interaction of 3-O-sulfotransferase isoform 1 with heparan sulfateExpression of low endotoxin 3-O-sulfotransferase in Bacillus subtilis and Bacillus megaterium.Engineered heparins as new anticoagulant drugs.
P2860
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P2860
Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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name
Crystal structure and mutation ...... -O-sulfotransferase isoform 1.
@en
Crystal structure and mutation ...... -O-sulfotransferase isoform 1.
@nl
type
label
Crystal structure and mutation ...... -O-sulfotransferase isoform 1.
@en
Crystal structure and mutation ...... -O-sulfotransferase isoform 1.
@nl
prefLabel
Crystal structure and mutation ...... -O-sulfotransferase isoform 1.
@en
Crystal structure and mutation ...... -O-sulfotransferase isoform 1.
@nl
P2093
P2860
P356
P1476
Crystal structure and mutation ...... -O-sulfotransferase isoform 1.
@en
P2093
Karen A Lee
Lars C Pedersen
Masahiko Negishi
Suzanne C Edavettal
P2860
P304
25789-25797
P356
10.1074/JBC.M401089200
P407
P577
2004-04-01T00:00:00Z