Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain. - Wikidata - awgldk - TriplyDB

Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain.

Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain.

http://www.wikidata.org/entity/Q44855428

about

Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair Precision Medicine in Multiple Sclerosis: Future of PET Imaging of Inflammation and Reactive Astrocytes In vivo imaging of neuroinflammation in schizophrenia Binding of NIR-conPK and NIR-6T to astrocytomas and microglial cells: evidence for a protein related to TSPO.Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans.Autoradiography screening of potential positron emission tomography tracers for asymptomatic abdominal aortic aneurysms Radiation dosimetry and biodistribution of the translocator protein radiotracer [(11)C]DAA1106 determined with PET/CT in healthy human volunteers.A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation.Effect of Cigarette Smoking on a Marker for Neuroinflammation: A [11C]DAA1106 Positron Emission Tomography Study.Image derived input function for [18F]-FEPPA: application to quantify translocator protein (18 kDa) in the human brain.Evaluation of [(11)C]CB184 for imaging and quantification of TSPO overexpression in a rat model of herpes encephalitis.In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders.The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging.The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds to activated and infected brain macrophages in areas of synaptic degeneration: implications for PET imaging of neuroinflammation in lentiviral encephalitis Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation.Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors In vivo evidence for microglial activation in neurodegenerative dementia.Animal models of tauopathies.The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging.A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation Positron emission tomography imaging of neuroinflammation.Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.Microglia and inflammation in Alzheimer's disease.Molecular imaging of dementia.The role of neuroinflammation in dementias.Positron-emission tomography molecular imaging of glia and myelin in drug discovery for multiple sclerosis.Assessing brain immune activation in psychiatric disorders: clinical and preclinical PET imaging studies of the 18-kDa translocator protein.Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects.Peripheral benzodiazepine receptors in patients with chronic schizophrenia: a PET study with [11C]DAA1106.Sifting through the surfeit of neuroinflammation tracers.Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging in Neurological Diseases.In vivo imaging of the 18-kDa translocator protein (TSPO) with [18F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients.Copper-mediated aromatic radiofluorination revisited: efficient production of PET tracers on a preparative scale.Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [(11)C]DAA1106.Evaluation of reference regions for (R)-[(11)C]PK11195 studies in Alzheimer's disease and mild cognitive impairment.Enhanced copper-mediated (18)F-fluorination of aryl boronic esters provides eight radiotracers for PET applications.Characterization of a novel acetamidobenzoxazolone-based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain.

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P2860

Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain.

http://www.wikidata.org/entity/Q44855428

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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name

Novel peripheral benzodiazepin ...... for glial cells in the brain.

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Novel peripheral benzodiazepin ...... for glial cells in the brain.

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type

label

Novel peripheral benzodiazepin ...... for glial cells in the brain.

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Novel peripheral benzodiazepin ...... for glial cells in the brain.

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prefLabel

Novel peripheral benzodiazepin ...... for glial cells in the brain.

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Novel peripheral benzodiazepin ...... for glial cells in the brain.

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Novel peripheral benzodiazepin ...... for glial cells in the brain.

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P2093

Akihiro Takano

http://www.w3.org/2001/XMLSchema#string

Fumihiko Yasuno

http://www.w3.org/2001/XMLSchema#string

Jun Maeda

http://www.w3.org/2001/XMLSchema#string

Kazutoshi Suzuki

http://www.w3.org/2001/XMLSchema#string

Ming-Rong Zhang

http://www.w3.org/2001/XMLSchema#string

Motoki Inaji

http://www.w3.org/2001/XMLSchema#string

Shigeru Obayashi

http://www.w3.org/2001/XMLSchema#string

Takashi Okauchi

http://www.w3.org/2001/XMLSchema#string

Tetsuya Suhara

http://www.w3.org/2001/XMLSchema#string

Yoko Ikoma

http://www.w3.org/2001/XMLSchema#string

P2860

Thalamic microglial activation in ischemic stroke detected in vivo by PET and [11C]PK1195.

The distribution of radioactivity in brains of rats given [N-methyl-11C]PK 11195 in vivo after induction of a cortical ischaemic lesion.

Macrophage and astrocyte populations in relation to [3H]PK 11195 binding in rat cerebral cortex following a local ischaemic lesion.

Imaging cerebral vasculitis in refractory epilepsy using [(11)C](R)-PK11195 positron emission tomography.

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scholarly article

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10.1002/SYN.20027

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4

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52

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2004-06-01T00:00:00Z

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15103694

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