Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals.
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Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic proteinAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune DiseasesOverview of Traumatic Brain Injury: An Immunological ContextBacterial and viral superantigens: roles in autoimmunity?On-chip activation and subsequent detection of individual antigen-specific T cells.Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors.Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patientsHLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course.Myelin basic protein-specific T lymphocyte repertoire in multiple sclerosis. Complexity of the response and dominance of nested epitopes due to recruitment of multiple T cell clonesStructure of human T-cell receptors specific for an immunodominant myelin basic protein peptide: positioning of T-cell receptors on HLA-DR2/peptide complexes.Epitopes on the beta subunit of human muscle acetylcholine receptor recognized by CD4+ cells of myasthenia gravis patients and healthy subjects.In healthy primates, circulating autoreactive T cells mediate autoimmune disease.Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types.Myelin basic protein induces neuron-specific toxicity by directly damaging the neuronal plasma membrane.Experimental allergic encephalomyelitis in cynomolgus monkeys. Quantitation of T cell responses in peripheral blood.Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy.Mannosylated Linear and Cyclic Single Amino Acid Mutant Peptides Using a Small 10 Amino Acid Linker Constitute Promising Candidates Against Multiple Sclerosis.Identification of thyroid stimulating hormone receptor-specific T cells in Graves' disease thyroid using autoantigen-transfected Epstein-Barr virus-transformed B cell lines.Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigensMultiparameter Flow Cytometric Assays to Quantify Effector and Regulatory T-Cell Function in Multiple SclerosisAutoreactive CD8+ T-cell responses to human myelin protein-derived peptidesDQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP).Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis.A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosisIncreased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis.Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha productionVisualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex.Direct ex vivo analysis of activated, Fas-sensitive autoreactive T cells in human autoimmune disease.In vivo survival of viral antigen-specific T cells that induce experimental autoimmune encephalomyelitis.Multiple sclerosis patients show sexual dimorphism in cytokine responses to myelin antigens.Thymic expression of peripheral tissue antigens in humans: a remarkable variability among individualsDifferential induction of experimental autoimmune encephalomyelitis by myelin basic protein molecular mimics in mice humanized for HLA-DR2 and an MBP(85-99)-specific T cell receptor.Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disordersMultiple sclerosis and regulatory T cells.Treatment of experimental encephalomyelitis with a novel chimeric fusion protein of myelin basic protein and proteolipid protein.Immunodominance of a low-affinity major histocompatibility complex-binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire.Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2-restricted T cell clones from multiple sclerosis patients. Identity of key contact residues in the B-cell and T-cell epitopes.Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells.Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis.The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis
P2860
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P2860
Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
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1990年學術文章
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name
Fine specificity and HLA restr ...... ients and healthy individuals.
@en
Fine specificity and HLA restr ...... ients and healthy individuals.
@nl
type
label
Fine specificity and HLA restr ...... ients and healthy individuals.
@en
Fine specificity and HLA restr ...... ients and healthy individuals.
@nl
prefLabel
Fine specificity and HLA restr ...... ients and healthy individuals.
@en
Fine specificity and HLA restr ...... ients and healthy individuals.
@nl
P2093
P921
P1476
Fine specificity and HLA restr ...... ients and healthy individuals.
@en
P2093
Flerlage M
Jaraquemada D
McFarland HF
McFarlin DE
Whitaker J
P304
P407
P577
1990-07-01T00:00:00Z