Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein.
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Energy metabolism in the liverProtein lysine acetylation by p300/CBPAdaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat SpalaxCREB binding protein (CBP) activation is required for luteinizing hormone beta expression and normal fertility in micePotential biomarker of metformin action.Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression.CREB and the CRTC co-activators: sensors for hormonal and metabolic signalsThe regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1).Integrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver.Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activationAbsence of the glucagon-like peptide-1 receptor does not affect the metabolic phenotype of mice with liver-specific G(s)α deficiency.Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic controlHigher protein kinase C ζ in fatty rat liver and its effect on insulin actions in primary hepatocytesNeuroendocrine and metabolic components of dopamine agonist amelioration of metabolic syndrome in SHR ratsHepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses.Is histone acetylation the most important physiological function for CBP and p300?Transcriptional co-activator p300 maintains basal hepatic gluconeogenesis.Emerging role of mutations in epigenetic regulators including MLL2 derived from The Cancer Genome Atlas for cervical cancer.Targeting glycogen synthase kinase-3 in insulin signalling.Expression of epigenetic machinery genes is sensitive to maternal obesity and weight loss in relation to fetal growth in mice.Impact of oxidative stress and peroxisome proliferator-activated receptor gamma coactivator-1alpha in hepatic insulin resistance.Exendin-4 stimulation of cyclin A2 in beta-cell proliferation.Activation of basal gluconeogenesis by coactivator p300 maintains hepatic glycogen storage.NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon actionMitochondrial (dys)function in adipocyte (de)differentiation and systemic metabolic alterations.Differential regulation of glycogenolysis by mutant protein phosphatase-1 glycogen-targeting subunits.Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein.Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases.Transcriptional regulation of energy metabolism in the liver.Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein.Protein acetylation in metabolism - metabolites and cofactors.Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions.Reduced Insulin Receptor Expression Enhances Proximal Tubule Gluconeogenesis.Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.Inhibition of lysine acetyltransferase KAT3B/p300 activity by a naturally occurring hydroxynaphthoquinone, plumbagin.The Genetic Basis of Type 2 Diabetes.Protein kinase B activity is sufficient to mimic the effect of insulin on glucagon gene transcription.Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3.GCN5L1 modulates cross-talk between mitochondria and cell signaling to regulate FoxO1 stability and gluconeogenesis.
P2860
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P2860
Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Insulin regulation of hepatic ...... ation of CREB-binding protein.
@en
Insulin regulation of hepatic ...... ation of CREB-binding protein.
@nl
type
label
Insulin regulation of hepatic ...... ation of CREB-binding protein.
@en
Insulin regulation of hepatic ...... ation of CREB-binding protein.
@nl
prefLabel
Insulin regulation of hepatic ...... ation of CREB-binding protein.
@en
Insulin regulation of hepatic ...... ation of CREB-binding protein.
@nl
P2093
P2860
P356
P1433
P1476
Insulin regulation of hepatic ...... ation of CREB-binding protein.
@en
P2093
Delia Porras
Fredric E Wondisford
Hesheng Ou
Karla Temple
Karuna Naik
Kelly Kaihara
Matthew J Brady
Michael W Roe
Nobuyuki Shibusawa
Xiao Yan Zhou
P2860
P2888
P304
P356
10.1038/NM1050
P407
P577
2004-05-16T00:00:00Z