Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations. - Wikidata - awgldk - TriplyDB

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

http://www.wikidata.org/entity/Q44902948

about

Meningioma Genomics: Diagnostic, Prognostic, and Therapeutic Applications.Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade.Molecular Testing of Brain Tumor.PET Imaging in Patients with Meningioma - Report of the RANO/PET Group.Genetic profiling by single-nucleotide polymorphism-based array analysis defines three distinct subtypes of orbital meningioma Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma Genetic/molecular alterations of meningiomas and the signaling pathways targeted.Pathology and molecular genetics of meningioma: recent advances.KLF4 regulates adult lung tumor-initiating cells and represses K-Ras-mediated lung cancer.Exome sequencing on malignant meningiomas identified mutations in neurofibromatosis type 2 (NF2) and meningioma 1 (MN1) genes.Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney.TERT Promoter Mutations and Risk of Recurrence in Meningioma.ARID1A and TERT promoter mutations in dedifferentiated meningioma.Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas.Overexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathway.The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor.Molecular Transition of an Adult Low-Grade Brain Tumor to an Atypical Teratoid/Rhabdoid Tumor Over a Time-Course of 14 Years.Diagnostic Challenges in Meningioma.Classification of human meningiomas: lights, shadows, and future perspectives.Genetic landscape of meningioma.The Emerging Role of TRAF7 in Tumor Development.The new WHO 2016 classification of brain tumors-what neurosurgeons need to know.BAP1 mutations in high-grade meningioma: implications for patient care.AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry.Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5.Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation.Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas.Clinical features, surgical management, and prognostic factors of secretory meningiomas: a single-center case series of 149 patients.Genomic analysis reveals frequent TRAF7 mutations in intraneural perineuriomas.Diffuse midline skull base meningiomas: identification of a rare and aggressive subgroup of meningiomas.Clinicopathological and molecular characteristics of pediatric meningiomas.High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression.[Tumors of the inner ear and adjacent structures].Frequent AKT1E17K mutations in skull base meningiomas are associated with mTOR and ERK1/2 activation and reduced time to tumor recurrence.Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein.KLF4 is a tumor suppressor in anaplastic meningioma stem-like cells and human meningiomas.Clinical impact of targeted amplicon sequencing for meningioma as a practical clinical-sequencing system.SMO mutant olfactory groove meningiomas-the next in line for targeted therapy.Epithelial differentiation with microlumen formation in meningioma: diagnostic utility of NHERF1/EBP50 immunohistochemistry.

P2860

Q26741529-2DAAB518-F1D3-4472-B6F9-97B2BA4A06B2 Q27853347-32AE4703-9055-4ADF-B863-BE0BDB0BACE9 Q33729693-C74F6FD4-A198-42F9-9FD3-B0DD7F6B5EA3 Q34682187-3B7F7E4A-0E88-4153-9605-219422CA389F Q35072568-979D07A1-0893-4B27-9C17-6C4945E5C3FC Q35741539-87C63C78-7B2A-4FDA-834F-0BDAF3F536DA Q35793582-29D57054-27A5-46E5-8ECF-608C220E96D5 Q35943650-9C38F818-E928-42BF-8D60-B9718AA12606 Q36472473-76A1BB35-C899-4733-88F8-D72E48B27996 Q36483721-A9715204-AED8-41C9-A025-4C62E0C1B1C5 Q36785144-6E87D88C-3D5B-4C2C-B161-101E9B06EE0C Q36807618-E33975E7-4F69-4A15-B287-30BE4432A6E0 Q36849156-F9EBEA59-BE1E-4D12-8622-B16340841C58 Q36942228-41477BCB-A79E-4F65-B39B-E7AC959AF0D2 Q37420954-8EF76BA8-5A99-4919-855B-B79A3E120A63 Q37645016-3422A35F-1D68-472A-BF0D-AE05D3B44648 Q38565718-52BB3F5F-321D-4C18-AE11-D73C6B6E48F3 Q38633637-7DE3CF1E-F6CA-4334-99FD-D4E20A4FFDFB Q38680767-019936F2-52BA-4193-B18B-FB3834A48F0E Q38810583-DDFEBA6E-9797-493F-B88F-81149EC6ED31 Q38953562-8010AAEF-6C48-4AE0-9B09-48CAAB348A80 Q38997320-0197C462-CB54-4893-87A6-38A0B5A79181 Q39091307-6E8228AF-452A-4F6F-8D84-313C5F69A52F Q39290955-5BD83488-A126-4534-8E9D-DCD959B8CD80 Q42445998-11924D98-C520-4DF4-BB0A-AC1104BD2643 Q43084857-33F7B232-1C11-457E-9B31-4E4079003677 Q45997283-E655B0A0-F21F-4E31-A8F4-9E6C420DF45E Q46129842-BC76E463-6FA7-4D8E-AE43-EAB8361A639A Q47578132-DA2B3E28-7293-4F46-86D3-22A6C2DF6465 Q48030508-967FFAF0-2F89-4BD9-AEE5-978D81973946 Q48109121-A202099F-DB53-4137-B57E-A2CEB7BA73B2 Q48355463-2DD2DFCE-940A-428F-BF74-E971374B6568 Q48857394-0C5D2EB0-BCE1-4DC5-8585-451A5407CF29 Q50217988-09307757-BD15-4248-92DA-0F2B0BA98490 Q50664835-52775891-5687-40B3-B625-4B97771FE07A Q51075492-10493B44-B553-47B4-BE19-DA7F5A6CAC39 Q52764536-1FA0E08F-8276-4D3D-B1CF-A1D8F2AA1F0B Q53117505-868CB1C9-DD0B-4E23-B511-0EC505060127 Q53971614-5A9ECEB6-6FFE-4AED-84E5-6D486E29F998 Q55456657-B2808442-AFC0-4902-A7E8-C05FF20E13F6

P2860

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

http://www.wikidata.org/entity/Q44902948

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年学术文章

@wuu

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh

2013年學術文章

@zh-hant

name

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

@en

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

@nl

type

label

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

@en

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

@nl

prefLabel

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

@en

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

@nl

P1433

Q44902948-42D0E8CC-2B24-4521-9C60-DDE205379DD8

P1476

Q44902948-8C445547-1B7B-4FFD-96B1-F7CC357C8166

P2093

Q44902948-03DD0DD5-86A7-490F-85EF-5B28200CB29D

Q44902948-058AB8D8-12A1-4EAD-B126-B68AF7173928

Q44902948-0DB40F01-E096-4E67-88BC-E6957B9E47BB

Q44902948-249A8DAF-07C5-46A4-BD7F-564E1ADC4806

Q44902948-27A225D7-B29F-4312-9C90-FB9AF2E3B6B8

Q44902948-35ECFEC8-3AB7-4B58-82E9-8A84270DB258

Q44902948-38676325-37E0-4BC6-96FF-FB0A14103BC1

Q44902948-38773509-697A-4646-A4B4-97A97D84D559

Q44902948-46C095E8-6A68-41A4-9806-4318031F6ADC

Q44902948-51CDEDCB-0AD2-4175-A31A-1A6E43737243

P2860

Q44902948-14BA8FFE-8142-4887-AC14-4659BAF39A54

Q44902948-171CDAAB-BFA3-47AF-A675-DE632C7B38FE

Q44902948-18F32DAD-B437-48FF-9F66-D723A0B054B4

Q44902948-1D8FEA0C-636F-4E40-8DE6-CA26E6795AC6

Q44902948-250584F4-6842-4138-A463-2EA2088D4400

Q44902948-2C818848-590F-4DE1-B2DD-69B16E126F12

Q44902948-32F68059-F3FE-4049-AAE1-48BCF7CE1852

Q44902948-3F7D94AE-8639-4C12-8537-A3016C21B273

Q44902948-46BEAF1F-A122-44ED-80B3-1CD8296B48AF

Q44902948-585CF355-CB99-4BF7-9D48-FAFB368E6AA4

P2888

Q44902948-489AE3C5-8B48-41EA-9B31-F9FA28E63D57

P304

Q44902948-5DD10B95-5BFF-4317-933A-799D37049ABF

P31

Q44902948-28C76945-65CB-4A5D-8B22-AF1395B3A2FF

P356

Q44902948-6295D4D0-0F0C-40C7-ADAB-EC820DA5F95B

P433

Q44902948-EB220CEE-6C4C-4A74-AC3B-A05903E44789

P478

Q44902948-2C885765-6006-4BFF-9EB9-2CDF26BF1A3A

P50

Q44902948-1A54F120-A57A-4C1D-A331-2A7BDF995D0E

Q44902948-29B55B19-B580-40D7-80FF-DA110EBC4CEB

Q44902948-4A7B959A-15BE-4B57-A906-46E89B2E24B3

Q44902948-5399562B-236E-4417-84B0-F5A3F0713085

Q44902948-776824E9-72AB-4B19-B21A-101A7B7EA720

Q44902948-92697920-BE7B-4C57-8449-21AAB6B86FAF

Q44902948-B574ACA3-CD03-4F28-AE39-7BD20AB489CF

Q44902948-DA7E5D46-4276-4288-8AB5-26788CA023B7

Q44902948-E12C03C8-D50A-4CBE-80EC-642FED3AAA4D

Q44902948-FE76BD35-1D74-460F-A11A-7200A10B044C

P577

Q44902948-9C6A72BB-D142-42E7-8062-3892F845DCB6

P698

Q44902948-2E6BBCAD-DBE6-4375-944F-1FB544A0AE9C

P356

S00401-013-1093-X

P1433

Acta Neuropathologica

P1476

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

@en

P2093

Albert Becker

http://www.w3.org/2001/XMLSchema#string

Christian Hagenlocher

http://www.w3.org/2001/XMLSchema#string

Christian Hartmann

http://www.w3.org/2001/XMLSchema#string

Christian Koelsche

http://www.w3.org/2001/XMLSchema#string

Christian Mawrin

http://www.w3.org/2001/XMLSchema#string

David E Reuss

http://www.w3.org/2001/XMLSchema#string

David T W Jones

http://www.w3.org/2001/XMLSchema#string

Doris Lenartz

http://www.w3.org/2001/XMLSchema#string

Jana Mucha

http://www.w3.org/2001/XMLSchema#string

Jochen Meyer

http://www.w3.org/2001/XMLSchema#string

P2860

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

Mammalian Krüppel-like factors in health and diseases

Dissecting the genomic complexity underlying medulloblastoma

Fast and accurate short read alignment with Burrows-Wheeler transform

The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

The Sequence Alignment/Map format and SAMtools

Combinatorial control of the bradykinin B2 receptor promoter by p53, CREB, KLF-4, and CBP: implications for terminal nephron differentiation

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

Secretory meningiomas: a benign subgroup causing life-threatening complications

P2888

s00401-013-1093-x

P304

351-358

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S00401-013-1093-X

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

125

http://www.w3.org/2001/XMLSchema#string

P50

Stefan M Pfister

Andreas von Deimling

Christel Herold-Mende

Rosario M. Piro

P Andrew Futreal

P577

2013-02-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23404370

http://www.w3.org/2001/XMLSchema#string