Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.
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Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentrationAMPK: a cellular metabolic and redox sensor. A minireviewMetabolic shifts during aging and pathologyCardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overloadThiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell deathExpression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophyImpaired overload-induced muscle growth is associated with diminished translational signalling in aged rat fast-twitch skeletal muscleAdenosine kinase regulation of cardiomyocyte hypertrophy.MEF2C silencing attenuates load-induced left ventricular hypertrophy by modulating mTOR/S6K pathway in miceAdiponectin-mediated modulation of hypertrophic signals in the heartAdiponectin actions in the cardiovascular system.The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse.Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.Impaired overload-induced hypertrophy is associated with diminished mTOR signaling in insulin-resistant skeletal muscle of the obese Zucker ratTumor Suppressor Serine/Threonine Kinase LKB1 Expression, Not Kinase Activity, Increased in the Vascular Smooth Muscle Cells and Neointima in the Rat Carotid Artery Injury ModelMetformin and sex: Why suppression of aging may be harmful to young male mice.Regulation of mRNA translation in renal physiology and disease.Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart.Regulation of AMPK by the ubiquitin proteasome systemTargeted deletion of PTEN in cardiomyocytes renders cardiac contractile dysfunction through interruption of Pink1-AMPK signaling and autophagyAMPK in cardiovascular health and disease.Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathwaysAdiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling.Metformin attenuates myocardial remodeling and neutrophil recruitment after myocardial infarction in rat.Mitochondrial oxidative stress corrupts coronary collateral growth by activating adenosine monophosphate activated kinase-α signaling.The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling.EGCG Blocked Phenylephrin-Induced Hypertrophy in H9C2 Cardiomyocytes, by Activating AMPK-Dependent PathwayAMP-activated protein kinase regulates E3 ligases in rodent heart.A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway.Signaling mechanisms in the regulation of renal matrix metabolism in diabetes.Transient activation of p38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPKAMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.Activation of AMP-activated protein kinase (AMPK) inhibits protein synthesis: a potential strategy to prevent the development of cardiac hypertrophy.Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes.Global protein synthesis in human trophoblast is resistant to inhibition by hypoxia.Adiponectin gene therapy ameliorates high-fat, high-sucrose diet-induced metabolic perturbations in mice.Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise.AMPK alterations in cardiac physiology and pathology: enemy or ally?AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy.Testosterone regulation of Akt/mTORC1/FoxO3a signaling in skeletal muscle.
P2860
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P2860
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Activation of AMP-activated pr ...... trophy in the cardiac myocyte.
@en
Activation of AMP-activated pr ...... trophy in the cardiac myocyte.
@nl
type
label
Activation of AMP-activated pr ...... trophy in the cardiac myocyte.
@en
Activation of AMP-activated pr ...... trophy in the cardiac myocyte.
@nl
prefLabel
Activation of AMP-activated pr ...... trophy in the cardiac myocyte.
@en
Activation of AMP-activated pr ...... trophy in the cardiac myocyte.
@nl
P2093
P356
P1476
Activation of AMP-activated pr ...... trophy in the cardiac myocyte.
@en
P2093
Anita Y M Chan
Carrie-Lynn M Soltys
Jason R B Dyck
Martin E Young
P304
32771-32779
P356
10.1074/JBC.M403528200
P407
P577
2004-05-24T00:00:00Z