TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function. - Wikidata - awgldk - TriplyDB

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

http://www.wikidata.org/entity/Q44912776

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Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function Triggering receptor expressed on myeloid cells receptor family modulators: a patent review Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12 Siglec-15 protein regulates formation of functional osteoclasts in concert with DNAX-activating protein of 12 kDa (DAP12)Bone microenvironment specific roles of ITAM adapter signaling during bone remodeling induced by acute estrogen-deficiency.The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.CD16 (FcRgammaIII) as a potential marker of osteoclast precursors in psoriatic arthritis Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP).Efficient and stable gene expression into human osteoclasts using an HIV-1-based lentiviral vector Macrophage metalloelastase (MMP-12) deficiency mitigates retinal inflammation and pathological angiogenesis in ischemic retinopathy.Denosumab: targeting the RANKL pathway to treat rheumatoid arthritis.Inactivation of DAP12 in PMN inhibits TREM1-mediated activation in rheumatoid arthritis The C-type lectin OCILRP2 costimulates EL4 T cell activation via the DAP12-Raf-MAP kinase pathway.The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease RNA therapeutics targeting osteoclast-mediated excessive bone resorption.Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.MicroRNA-125b-5p suppresses Brucella abortus intracellular survival via control of A20 expression.The TREM2-DAP12 signaling pathway in Nasu-Hakola disease: a molecular genetics perspective.Nucleosides accelerate inflammatory osteolysis, acting as distinct innate immune activators.E proteins regulate osteoclast maturation and survival.Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function The TREM receptor family and signal integration.The innate immune response to Salmonella enterica serovar Typhimurium by macrophages is dependent on TREM2-DAP12 The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints.TREM2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis.Osteoclasts - the innate immune cells of the bone.Alternative macrophage activation in periprosthetic osteolysis.Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression.Cross-regulation of signaling by ITAM-associated receptors.TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.TREM-2 promotes acquired cholesteatoma-induced bone destruction by modulating TLR4 signaling pathway and osteoclasts activation.A physical interaction between the adaptor proteins DOK3 and DAP12 is required to inhibit lipopolysaccharide signaling in macrophages.Mechanism and function of monoclonal antibodies targeting siglec-15 for therapeutic inhibition of osteoclastic bone resorption.Osteoimmunology: the expanding role of immunoreceptors in osteoclasts and bone remodeling A Comprehensive Review of Immunoreceptor Regulation of Osteoclasts.TREM2 in Neurodegenerative Diseases.

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P2860

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

http://www.wikidata.org/entity/Q44912776

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

@en

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

@nl

type

label

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

@en

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

@nl

prefLabel

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

@en

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

@nl

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Journal of Bone and Mineral Research

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TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.

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Eréne C Niemi

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James A Torchia

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Lewis L Lanier

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Mary Beth Humphrey

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Mary C Nakamura

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Michael R Daws

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Steve C Spusta

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William E Seaman

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237-245

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scholarly article

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10.1359/JBMR.051016

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2

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21

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16418779

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Triggering receptor expressed on myeloid cells 2