Alterations in lipid raft composition and dynamics contribute to abnormal T cell responses in systemic lupus erythematosus.
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Small molecules in the treatment of systemic lupus erythematosusRegulation of Adaptive Immunity in Health and Disease by Cholesterol MetabolismFcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) ExpressionThe pathology of T cells in systemic lupus erythematosusSystems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.Differential calcium signaling and Kv1.3 trafficking to the immunological synapse in systemic lupus erythematosusT-cell and B-cell signaling biomarkers and treatment targets in lupus.T cell CD3ζ deficiency enables multiorgan tissue inflammation.T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells.Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunityLowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage.Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradationReducing FLI1 levels in the MRL/lpr lupus mouse model impacts T cell function by modulating glycosphingolipid metabolismCalcium signaling in systemic lupus erythematosus T cells: a treatment targetAbnormalities of T cell signaling in systemic lupus erythematosus.Systemic lupus erythematosus: from genes to organ damage.T cell activation by terminal complex of complement and immune complexes.Accelerated vascular disease in systemic lupus erythematosus: role of macrophage.Effect of Leflunomide on the Abnormal Expression of Lipid Rafts and F-Actin in B Lymphocytes from Patients with Systemic Lupus ErythematosusT cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity.Regulation of T-cell receptor signalling by membrane microdomains.T-helper cell intrinsic defects in lupus that break peripheral tolerance to nuclear autoantigens.Molecular basis for T cell response induced by altered peptide ligand of type II collagen.Statins: immunomodulators for autoimmune rheumatic disease?New insights into the pathogenesis of systemic lupus erythematosus.Lipid rafts in T cell receptor signallingSystems biology in systemic lupus erythematosus: integrating genes, biology and immune function.Altered dynamics of Kv1.3 channel compartmentalization in the immunological synapse in systemic lupus erythematosusCholera toxin B accelerates disease progression in lupus-prone mice by promoting lipid raft aggregation.Lipid rafts in T cell signalling and disease.Systemic lupus erythematosus: new molecular targets.Differential expression and molecular associations of Syk in systemic lupus erythematosus T cells.Agrin signalling contributes to cell activation and is overexpressed in T lymphocytes from lupus patients.Novel molecular targets in the treatment of systemic lupus erythematosus.Biomarkers in systemic lupus erythematosus: challenges and prospects for the future.PP2A dephosphorylates Elf-1 and determines the expression of CD3zeta and FcRgamma in human systemic lupus erythematosus T cells.Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE.Lipids rule: resetting lipid metabolism restores T cell function in systemic lupus erythematosus.Metabolic Factors that Contribute to Lupus PathogenesisEndogenous retroviral pathogenesis in lupus.
P2860
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P2860
Alterations in lipid raft composition and dynamics contribute to abnormal T cell responses in systemic lupus erythematosus.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Alterations in lipid raft comp ...... systemic lupus erythematosus.
@en
Alterations in lipid raft comp ...... systemic lupus erythematosus.
@nl
type
label
Alterations in lipid raft comp ...... systemic lupus erythematosus.
@en
Alterations in lipid raft comp ...... systemic lupus erythematosus.
@nl
prefLabel
Alterations in lipid raft comp ...... systemic lupus erythematosus.
@en
Alterations in lipid raft comp ...... systemic lupus erythematosus.
@nl
P2093
P1476
Alterations in lipid raft comp ...... systemic lupus erythematosus.
@en
P2093
Carolyn U Fisher
George C Tsokos
Jeanne Mitchell
Madhusoodana P Nambiar
Nancy Delaney
Sandeep Krishnan
Vishal G Warke
P304
P356
10.4049/JIMMUNOL.172.12.7821
P407
P577
2004-06-01T00:00:00Z