Identification of the residues in human CD4 critical for the binding of HIV.
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Structural features of nectin-2 (HveB) required for herpes simplex virus entryComparative investigation of Langerhans' cells and potential receptors for HIV in oral, genitourinary and rectal epitheliaIdentification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex moleculesPathogenesis of human immunodeficiency virus infectionGlycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 bindingRole of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infectionRational engineering of a miniprotein that reproduces the core of the CD4 site interacting with HIV-1 envelope glycoproteinKinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 bindingRole of 14-3-3epsilon, c-Myc/Max, and Akt phosphorylation in HIV-1 gp 120-induced mesangial cell proliferationAnti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via gp120 V3 interactionsEffects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoproteinDirect evidence for native CD4 oligomers in lymphoid and monocytoid cells.CD4 and its role in infection of rabbit cell lines by human immunodeficiency virus type 1Anti-HIV agents targeting the interaction of gp120 with the cellular CD4 receptor.Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor.The Ixodes scapularis salivary protein, salp15, prevents the association of HIV-1 gp120 and CD4Effect of trimerization motifs on quaternary structure, antigenicity, and immunogenicity of a noncleavable HIV-1 gp140 envelope glycoprotein.Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 moleculeCyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals.Discovery of small-molecule human immunodeficiency virus type 1 entry inhibitors that target the gp120-binding domain of CD4.Mutational analysis of the virus and monoclonal antibody binding sites in MHVR, the cellular receptor of the murine coronavirus mouse hepatitis virus strain A59Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis.Novel peptides based on HIV-1 gp120 sequence with homology to chemokines inhibit HIV infection in cell culture.Lack of correlation between soluble CD4-induced shedding of the human immunodeficiency virus type 1 exterior envelope glycoprotein and subsequent membrane fusion events.Cyanovirin-N, a potent human immunodeficiency virus-inactivating protein, blocks both CD4-dependent and CD4-independent binding of soluble gp120 (sgp120) to target cells, inhibits sCD4-induced binding of sgp120 to cell-associated CXCR4, and dissociaInhibition of HIV-1 infection in ex vivo cervical tissue model of human vagina by palmitic acid; implications for a microbicide development.Crystallographic and cryo EM analysis of virion-receptor interactionsCrosslinked HIV-1 envelope-CD4 receptor complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaquesAmino acid substitutions in the V domain of nectin-1 (HveC) that impair entry activity for herpes simplex virus types 1 and 2 but not for Pseudorabies virus or bovine herpesvirus 1.Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoproteinFunctional domains of the poliovirus receptor.Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies.Crystal structure of an HIV-binding recombinant fragment of human CD4.Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras.Adaptation of subtype a human immunodeficiency virus type 1 envelope to pig-tailed macaque cellsTheoretical and practical aspects of antigenized antibodies.Virus receptors: implications for pathogenesis and the design of antiviral agents.Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences
P2860
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P2860
Identification of the residues in human CD4 critical for the binding of HIV.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Identification of the residues in human CD4 critical for the binding of HIV.
@en
Identification of the residues in human CD4 critical for the binding of HIV.
@nl
type
label
Identification of the residues in human CD4 critical for the binding of HIV.
@en
Identification of the residues in human CD4 critical for the binding of HIV.
@nl
prefLabel
Identification of the residues in human CD4 critical for the binding of HIV.
@en
Identification of the residues in human CD4 critical for the binding of HIV.
@nl
P2093
P1433
P1476
Identification of the residues in human CD4 critical for the binding of HIV.
@en
P2093
Chaikin MA
Clapham PR
Fornwald JA
McDougal JS
Pietropaolo C
Sattentau QJ
P304
P356
10.1016/0092-8674(89)90922-7
P407
P577
1989-05-01T00:00:00Z