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Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair1,N(2)-propanodeoxyguanosine adduct formation in aortic DNA following inhalation of acroleinRing-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4Quantitation of acrolein-derived (3-hydroxypropyl)mercapturic acid in human urine by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: effects of cigarette smokingEnvironmental-stress-induced Chromatin Regulation and its HeritabilityAcrolein- and 4-Aminobiphenyl-DNA adducts in human bladder mucosa and tumor tissue and their mutagenicity in human urothelial cells.Effect of carcinogenic acrolein on DNA repair and mutagenic susceptibility.Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkBMolecular mechanisms of acrolein toxicity: relevance to human diseaseSmoking and lung cancer--a new role for an old toxicant?Pathobiology and chemoprevention of bladder cancerDe novo malignancy after paediatric renal replacement therapy.Acute systemic accumulation of acrolein in mice by inhalation at a concentration similar to that in cigarette smokeDetection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humansMutagenicity and sequence specificity of acrolein-DNA adducts.Effect of CpG methylation at different sequence context on acrolein- and BPDE-DNA binding and mutagenesisCigarette side-stream smoke lung and bladder carcinogenesis: inducing mutagenic acrolein-DNA adducts, inhibiting DNA repair and enhancing anchorage-independent-growth cell transformation.Detection and quantitation of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human lung by liquid chromatography-electrospray ionization-tandem mass spectrometry.Determination of urine 3-HPMA, a stable acrolein metabolite in a rat model of spinal cord injuryFormation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRIA comparative 90-day toxicity study of allyl acetate, allyl alcohol and acrolein.Effects of epigallocatechin gallate, L-ascorbic acid, alpha-tocopherol, and dihydrolipoic acid on the formation of deoxyguanosine adducts derived from lipid peroxidation.Mechanisms Underlying Acrolein-Mediated Inhibition of Chromatin AssemblyChemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.Chemistry and structural biology of DNA damage and biological consequencesMutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adductsEndothelial dysfunction and claudin 5 regulation during acrolein-induced lung injury.Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family.Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury.
P2860
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P2860
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Acrolein initiates rat urinary bladder carcinogenesis.
@en
Acrolein initiates rat urinary bladder carcinogenesis.
@nl
type
label
Acrolein initiates rat urinary bladder carcinogenesis.
@en
Acrolein initiates rat urinary bladder carcinogenesis.
@nl
prefLabel
Acrolein initiates rat urinary bladder carcinogenesis.
@en
Acrolein initiates rat urinary bladder carcinogenesis.
@nl
P2093
P1433
P1476
Acrolein initiates rat urinary bladder carcinogenesis
@en
P2093
P304
P407
P577
1992-07-01T00:00:00Z