Detection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans
about
Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehydeEfficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappaAcrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair1,N(2)-propanodeoxyguanosine adduct formation in aortic DNA following inhalation of acroleinStereochemistry Modulates the Stability of Reduced Interstrand Cross-Links Arising from R - and S -α-CH 3 -γ-OH-1, N 2 -Propano-2‘-deoxyguanosine in the 5‘-CpG-3‘ DNA Sequence †Insertion of dNTPs Opposite the 1, N 2 -Propanodeoxyguanosine Adduct by Sulfolobus solfataricus P2 DNA Polymerase IV † ‡Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cellsMutagenicity of acrolein and acrolein-induced DNA adductsNutritional countermeasures targeting reactive oxygen species in cancer: from mechanisms to biomarkers and clinical evidenceMitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growthDetection of acrolein-derived cyclic DNA adducts in human cells by monoclonal antibodiesChronic oral exposure to the aldehyde pollutant acrolein induces dilated cardiomyopathyCharacterization of acrolein-glycerophosphoethanolamine lipid adducts using electrospray mass spectrometryDuplex DNA catalyzes the chemical rearrangement of a malondialdehyde deoxyguanosine adduct.Detection of 1,N(2)-propanodeoxyguanosine adducts in DNA of Fischer 344 rats by an adapted (32)P-post-labeling technique after per os application of crotonaldehyde.NMR characterization of a DNA duplex containing the major acrolein-derived deoxyguanosine adduct gamma -OH-1,-N2-propano-2'-deoxyguanosine.Evaluation of the mutagenic potential of the principal DNA adduct of acrolein.Repair kinetics of trans-4-hydroxynonenal-induced cyclic 1,N2-propanodeoxyguanine DNA adducts by human cell nuclear extractsMechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure.Oxidative modification of guanine bases initiated by oxyl radicals derived from photolysis of azo compounds.Oxyradicals and DNA damage.Nutrition and dietary carcinogens.γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage.DNA adducts: endogenous and induced.In vivo detection of a novel endogenous etheno-DNA adduct derived from arachidonic acid and the effects of antioxidants on its formation.Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa.Formation and repair of tobacco carcinogen-derived bulky DNA adductsAnalysis of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human leukocyte DNA from smokers and nonsmokers.Evolution of research on the DNA adduct chemistry of N-nitrosopyrrolidine and related aldehydes.Signaling actions of electrophiles: anti-inflammatory therapeutic candidatesMutagenic potency of exocyclic DNA adducts: marked differences between Escherichia coli and simian kidney cells.Photoreaction, phototoxicity, and photocarcinogenicity of retinoids.Mutagenicity and sequence specificity of acrolein-DNA adducts.Aldose reductase-catalyzed reduction of aldehyde phospholipidsMetabolism of the lipid peroxidation product, 4-hydroxy-trans-2-nonenal, in isolated perfused rat heart.Detection of the acrolein-derived cyclic DNA adduct by a quantitative 32P-postlabeling/solid-phase extraction/HPLC method: blocking its artifact formation with glutathione.Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta.Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and diseaseThe modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts.Detection and quantitation of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human lung by liquid chromatography-electrospray ionization-tandem mass spectrometry.
P2860
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P2860
Detection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Detection of exocyclic 1,N2-pr ...... lesions in rodents and humans
@ast
Detection of exocyclic 1,N2-pr ...... lesions in rodents and humans
@en
type
label
Detection of exocyclic 1,N2-pr ...... lesions in rodents and humans
@ast
Detection of exocyclic 1,N2-pr ...... lesions in rodents and humans
@en
prefLabel
Detection of exocyclic 1,N2-pr ...... lesions in rodents and humans
@ast
Detection of exocyclic 1,N2-pr ...... lesions in rodents and humans
@en
P2860
P356
P1476
Detection of exocyclic 1,N2-pr ...... lesions in rodents and humans
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.16.7491
P407
P577
1994-08-01T00:00:00Z