Expression of vaccinia virus K3L protein in yeast inhibits eukaryotic initiation factor-2 kinase GCN2 and the general amino acid control pathway.
about
Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stressHomologous regions of the alpha subunit of eukaryotic translational initiation factor 2 (eIF2alpha) and the vaccinia virus K3L gene product interact with the same domain within the dsRNA-activated protein kinase (PKR)Ribosome-binding domain of eukaryotic initiation factor-2 kinase GCN2 facilitates translation control.GCN2 phosphorylates HIV-1 integrase and decreases HIV-1 replication by limiting viral integration.A plant virus movement protein regulates the Gcn2p kinase in budding yeast.Regulation of the protein kinase PKR by the vaccinia virus pseudosubstrate inhibitor K3L is dependent on residues conserved between the K3L protein and the PKR substrate eIF2alpha.
P2860
Expression of vaccinia virus K3L protein in yeast inhibits eukaryotic initiation factor-2 kinase GCN2 and the general amino acid control pathway.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Expression of vaccinia virus K ...... al amino acid control pathway.
@en
Expression of vaccinia virus K ...... al amino acid control pathway.
@nl
type
label
Expression of vaccinia virus K ...... al amino acid control pathway.
@en
Expression of vaccinia virus K ...... al amino acid control pathway.
@nl
prefLabel
Expression of vaccinia virus K ...... al amino acid control pathway.
@en
Expression of vaccinia virus K ...... al amino acid control pathway.
@nl
P2093
P2860
P356
P1476
Expression of vaccinia virus K ...... al amino acid control pathway.
@en
P2093
P2860
P304
13202-13207
P356
10.1074/JBC.271.22.13202
P407
P577
1996-05-01T00:00:00Z