In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
about
Fed-state clamp stimulates cellular mechanisms of muscle protein anabolism and modulates glucose disposal in normal menEffect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activitycAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.Map4k4 negatively regulates peroxisome proliferator-activated receptor (PPAR) gamma protein translation by suppressing the mammalian target of rapamycin (mTOR) signaling pathway in cultured adipocytes.Altered regulation of contraction-induced Akt/mTOR/p70S6k pathway signaling in skeletal muscle of the obese Zucker rat.The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age.Glucagon acts in a dominant manner to repress insulin-induced mammalian target of rapamycin complex 1 signaling in perfused rat liverLipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside.Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells.mTORC1 signaling: what we still don't know.mTOR: more targets of resveratrol?cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.Whey protein ingestion activates mTOR-dependent signalling after resistance exercise in young men: a double-blinded randomized controlled trial.The mammalian target of rapamycin-p70 ribosomal S6 kinase but not phosphatidylinositol 3-kinase-Akt signaling is responsible for fibroblast growth factor-9-induced cell proliferation.Glucose stimulates protein synthesis in skeletal muscle of neonatal pigs through an AMPK- and mTOR-independent process.Developmental regulation of the activation of signaling components leading to translation initiation in skeletal muscle of neonatal pigs.
P2860
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P2860
In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
description
2004 nî lūn-bûn
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name
In rat hepatocytes glucagon in ...... ed by insulin and amino acids.
@en
In rat hepatocytes glucagon in ...... ed by insulin and amino acids.
@nl
type
label
In rat hepatocytes glucagon in ...... ed by insulin and amino acids.
@en
In rat hepatocytes glucagon in ...... ed by insulin and amino acids.
@nl
prefLabel
In rat hepatocytes glucagon in ...... ed by insulin and amino acids.
@en
In rat hepatocytes glucagon in ...... ed by insulin and amino acids.
@nl
P2093
P2860
P356
P1476
In rat hepatocytes glucagon in ...... ed by insulin and amino acids.
@en
P2093
Emmanuel Van Obberghen
John C Lawrence
Nadine Gautier
P2860
P304
42628-42637
P356
10.1074/JBC.M405173200
P407
P577
2004-08-02T00:00:00Z