cAMP-dependent oncogenic action of Rap1b in the thyroid gland. - Wikidata - awgldk - TriplyDB

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

http://www.wikidata.org/entity/Q45032460

about

Radixin assembles cAMP effectors Epac and PKA into a functional cAMP compartment: role in cAMP-dependent cell proliferation Loss of Rap1GAP in papillary thyroid cancer Rap1GAP inhibits tumor growth in oropharyngeal squamous cell carcinoma Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes Downregulation of Rap1GAP contributes to Ras transformation Lessons from mouse models of thyroid cancer.Modeling follicular thyroid cancer for future therapies Modeling thyroid cancer in the mouse.Mouse models of thyroid cancer: A 2015 update.Genetic alterations in thyroid cancer: the role of mouse models.miR-28-5p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B.A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation Epac, in synergy with cAMP-dependent protein kinase (PKA), is required for cAMP-mediated mitogenesis.Protein expression is altered during spontaneous sleep in aged Sprague Dawley rats.Elevated aggressive behavior in male mice with thyroid-specific Prkar1a and global Epac1 gene deletion.Cyclase-Associated Protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase.Cilostazol enhances integrin-dependent homing of progenitor cells by activation of cAMP-dependent protein kinase in synergy with Epac1.KRAS(G12D)-mediated oncogenic transformation of thyroid follicular cells requires long-term TSH stimulation and is regulated by SPRY1.

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P2860

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

http://www.wikidata.org/entity/Q45032460

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

@wuu

2004年学术文章

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2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

@yue

2004年學術文章

@zh

2004年學術文章

@zh-hant

name

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

@en

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

@nl

type

label

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

@en

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

@nl

prefLabel

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

@en

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

@nl

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P1433

Journal of Biological Chemistry

P1476

cAMP-dependent oncogenic action of Rap1b in the thyroid gland.

@en

P2093

Abraham Nyska

http://www.w3.org/2001/XMLSchema#string

Angelica Leon

http://www.w3.org/2001/XMLSchema#string

Daniel L Altschuler

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Fernando Ribeiro-Neto

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Julie Urbani-Brocard

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Liguang Lou

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P2860

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

A family of cAMP-binding proteins that directly activate Rap1

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

A ras-related gene with transformation suppressor activity

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

DOCK4, a GTPase activator, is disrupted during tumorigenesis

A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases

Dissemination and growth of cancer cells in metastatic sites

Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 cells induces DNA synthesis and morphological changes.

Ras and Rap1: two highly related small GTPases with distinct function.

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46868-46875

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scholarly article

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10.1074/JBC.M406858200

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P433

45

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P478

279

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2004-08-25T00:00:00Z

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P698

15331589

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